RNA polymerase II CTD tyrosine 1 is required for efficient termination by the Nrd1-Nab3-Sen1 pathway
In Saccharomyces cerevisiae, transcription termination at protein-coding genes is coupled to
the cleavage of the nascent transcript, whereas most non-coding RNA transcription relies on …
the cleavage of the nascent transcript, whereas most non-coding RNA transcription relies on …
The Nrd1–Nab3–Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domain
Abstract RNA polymerase II (Pol II) in Saccharomyces cerevisiae can terminate transcription
via several pathways. To study how a mechanism is chosen, we analyzed recruitment of …
via several pathways. To study how a mechanism is chosen, we analyzed recruitment of …
The role of Ctk1 kinase in termination of small non-coding RNAs
TL Lenstra, A Tudek, S Clauder, Z Xu, ST Pachis… - PLoS …, 2013 - journals.plos.org
Transcription termination in Saccharomyces cerevisiae can be performed by at least two
distinct pathways and is influenced by the phosphorylation status of the carboxy-terminal …
distinct pathways and is influenced by the phosphorylation status of the carboxy-terminal …
Termination of non‐coding transcription in yeast relies on both an RNA Pol II CTD interaction domain and a CTD‐mimicking region in Sen1
Z Han, O Jasnovidova, N Haidara, A Tudek… - The EMBO …, 2020 - embopress.org
Pervasive transcription is a widespread phenomenon leading to the production of a plethora
of non‐coding RNA s (nc RNA s) without apparent function. Pervasive transcription poses a …
of non‐coding RNA s (nc RNA s) without apparent function. Pervasive transcription poses a …
Cell-cycle modulation of transcription termination factor Sen1
Many non-coding transcripts (ncRNA) generated by RNA polymerase II in S. cerevisiae are
terminated by the Nrd1-Nab3-Sen1 complex. However, Sen1 helicase levels are …
terminated by the Nrd1-Nab3-Sen1 complex. However, Sen1 helicase levels are …
Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast
M Larochelle, MA Robert, JN Hébert, X Liu… - Nature …, 2018 - nature.com
Termination of RNA polymerase II (RNAPII) transcription is a fundamental step of gene
expression that is critical for determining the borders between genes. In budding yeast …
expression that is critical for determining the borders between genes. In budding yeast …
Pcf11 orchestrates transcription termination pathways in yeast
P Grzechnik, MR Gdula, NJ Proudfoot - Genes & development, 2015 - genesdev.cshlp.org
In Saccharomyces cerevisiae, short noncoding RNA (ncRNA) generated by RNA
polymerase II (Pol II) are terminated by the NRD complex consisting of Nrd1, Nab3, and …
polymerase II (Pol II) are terminated by the NRD complex consisting of Nrd1, Nab3, and …
Termination of transcription of short noncoding RNAs by RNA polymerase II
The RNA polymerase II transcription cycle is often divided into three major stages: initiation,
elongation, and termination. Research over the last decade has blurred these divisions and …
elongation, and termination. Research over the last decade has blurred these divisions and …
Interactions of Sen1, Nrd1, and Nab3 with multiple phosphorylated forms of the Rpb1 C-terminal domain in Saccharomyces cerevisiae
K Chinchilla, JB Rodriguez-Molina, D Ursic… - Eukaryotic …, 2012 - Am Soc Microbiol
The Saccharomyces cerevisiae SEN1 gene codes for a nuclear, ATP-dependent helicase
which is embedded in a complex network of protein-protein interactions. Pleiotropic …
which is embedded in a complex network of protein-protein interactions. Pleiotropic …
A bacterial-like mechanism for transcription termination by the Sen1p helicase in budding yeast
O Porrua, D Libri - Nature structural & molecular biology, 2013 - nature.com
Transcription termination is essential to generate functional RNAs and to prevent disruptive
polymerase collisions resulting from concurrent transcription. The yeast Sen1p helicase is …
polymerase collisions resulting from concurrent transcription. The yeast Sen1p helicase is …