[HTML][HTML] Is the Sex Difference a Clue to the Pathomechanism of Dry Eye Disease? Watch out for the NGF-TrkA-Piezo2 Signaling Axis and the Piezo2 Channelopathy
B Sonkodi, MD Resch, T Hortobágyi - Journal of Molecular Neuroscience, 2022 - Springer
Dry eye disease (DED) is a multifactorial disorder with recognized pathology, but not entirely
known pathomechanism. It is suggested to represent a continuum with neuropathic corneal …
known pathomechanism. It is suggested to represent a continuum with neuropathic corneal …
Corneal nerve loss is related to the severity of painful diabetic neuropathy
A Kalteniece, M Ferdousi, S Azmi… - European Journal of …, 2022 - Wiley Online Library
Background and purpose Previously it has been shown that patients with painful diabetic
neuropathy (PDN) have greater corneal nerve loss compared to patients with painless …
neuropathy (PDN) have greater corneal nerve loss compared to patients with painless …
[HTML][HTML] Could contact lens dryness discomfort symptoms sometimes have a neuropathic basis?
CW McMonnies - Eye and Vision, 2021 - Springer
Symptoms of dryness discomfort in soft contact lens wearers frequently lead to
discontinuation from wear. The negative influence of pre-fitting tear dysfunctions appears …
discontinuation from wear. The negative influence of pre-fitting tear dysfunctions appears …
Corneal neuropathic pain in irritable bowel syndrome: clinical findings and in vivo corneal confocal microscopy
Purpose Ocular discomfort is a common symptom in central sensitization syndromes. The
aim of this study was to evaluate ocular surface discomfort and related corneal changes in …
aim of this study was to evaluate ocular surface discomfort and related corneal changes in …
Corneal nerves in health and disease
BS Shaheen, M Bakir, S Jain - Survey of ophthalmology, 2014 - Elsevier
Corneal nerves are responsible for the sensations of touch, pain, and temperature and play
an important role in the blink reflex, wound healing, and tear production and secretion …
an important role in the blink reflex, wound healing, and tear production and secretion …
Successful management of corneal neuropathic pain with intrathecal targeted drug delivery
Objective. To describe the successful treatment of refractory corneal neuropathic pain with
neuromodulation techniques. Design. Single case report. Setting. Academic tertiary care …
neuromodulation techniques. Design. Single case report. Setting. Academic tertiary care …
[HTML][HTML] Corneal nerve abnormalities in painful dry eye disease patients
A Guerrero-Moreno, H Liang, N Moreau, J Luzu… - Biomedicines, 2021 - mdpi.com
Background: This study aimed to compare the corneal nerve structural abnormalities
detected using in vivo confocal microscopy (IVCM) in patients with neuropathic corneal pain …
detected using in vivo confocal microscopy (IVCM) in patients with neuropathic corneal pain …
The utilization of artificial intelligence for corneal nerve analyses of in vivo confocal microscopy images for the diagnosis of neuropathic corneal pain
ND Koseoglu, A Beam… - … Ophthalmology & Visual …, 2018 - iovs.arvojournals.org
Purpose: Neuropathic corneal pain (NCP) is one of the most underdiagnosed ocular surface
diseases due to lack of clinical signs explaining patients' symptoms. The presence of micro …
diseases due to lack of clinical signs explaining patients' symptoms. The presence of micro …
Ocular surface itch and pain: key differences and similarities between the two sensations
Ocular surface itch and pain: key differences and similariti... : Current Opinion in Allergy and
Clinical Immunology Ocular surface itch and pain: key differences and similarities between the …
Clinical Immunology Ocular surface itch and pain: key differences and similarities between the …
Topical pain control for corneal abrasions: A systematic review and meta‐analysis
CW Yu, A Kirubarajan, M Yau… - Academic …, 2021 - Wiley Online Library
Objectives Corneal abrasions are common ophthalmic presentations to emergency
departments. Among emergency physicians and ophthalmologists, there are highly variable …
departments. Among emergency physicians and ophthalmologists, there are highly variable …