Treatment of profound hyponatremia is challenging. Severe symptoms mandate correction
by 4 to 6 mEq/L within hours, but with risk factors for osmotic demyelination, daily correction …

Abstract Treatment of hypotonic hyponatremia often challenges clinicians on many counts.
Despite similar serum sodium concentrations, clinical manifestations can range from mild to …

Overly rapid correction of hyponatremia is defined as a plasma sodium correction rate
exceeding the recommended limits, but controversy still exists about what those limits are …

Rationale: Severe hyponatremia can lead to dramatic complications whether it is treated or
not. At times, it may be very severe (serum Na concentration: NaS< 115 mmol/L) or even …

Discussion The correct answer for this patient would be item C. This patient presents with
acute on CKD along with oliguria, volume overload, severe hyponatremia, and …

Taking into account the danger of provoking osmotic demyelination by causing an overly
rapid rise in the plasma sodium level, these authors from the University of Toronto offer their …

Acute hyponatremia or hypernatremia can cause brain damage. Correcting chronic
hyponatremia or hypernatremia too aggressively can do the same. A rapidly falling plasma …

ABSTRACT Hyponatremia (serum sodium< 135 mEq/L) is a common electrolyte disorder in
community or hospitalized patients. Serum sodium levels should be corrected at a proper …

Hyponatremia is a relatively common disorder occurring in up to 6% of hospitalized patients
and can occur through any mechanism that produces a relative excess of body water to …

In this Evidence-Based Nephrology review, Sterns (1) summarizes the available evidence
relating to the safety of treatment for severe symptomatic hyponatremia. The sources of …