The total synthesis of the diastereomeric amino acids 2 and their N-trideuteriomethyl
analogues has been carried out. These compounds represent possible intermediates along …

BIOSYNTHESIS OF ERGOT ALKALOIDS. THE ORIGIN OF THE N-METHYL GROUP Page 1
2936 CANADIAN JOURNAL OF CHEMISTRY. VOL. BIOSYNTHESIS OF ERGOT ALKALOIDS …

It is known that tryptophan and mevalonic acid serve as precursors in the biosynthesis of the
clavine alkaloids of ergot, which in turn are intermediates in the formation of the medically …

Ergot alkaloids, the metabolic products of various species of the parasitic fungus CIauiceps(
Clavicipitales), have many fascinating features which may account for the long-standing …

The biosynthesis of ergot alkaloids, eg, chanoclavine-I (I) and elymoclavine (II) from L-
tryptophan, methionine, and di-methylallyl pyrophosphate via Ar-methyl-4-(7, y-dimethylallyl) …

The synthetic strategies to the ergoline ring system (I) have been outlined, and discussed in
terms of their yields and limitations. The total syntheses of ergoline, racemic and natural …

Biosynthesis of Ergot Alkaloids. Enzymatic Closure of Ring D of the Ergolene Nucleus \ / Page
1 CHEMICAL COMMUNICATIONS, 1970 775 Biosynthesis of Ergot Alkaloids. Enzymatic …

Publisher Summary This chapter discusses that chemist of new group of alkaloids firmly
roots ergot alkaloids in the well-cultivated soil of alkaloid research. In the history and …

Incubation of cultures of Claviceps sp. strain SD 58 in an atmosphere of 1S02 gas and GC-
MS analysis of the resulting alkaloids showed that the oxygen atoms of both elymoclavine …

Tetrahedron Letters,Vo1.26,No.34,po 4043-4046,1985 0040-4039/85 $3.00 + .OO Printed in
Great Britain 81985 Pergamon Press Ltd. A Page 1 Tetrahedron Letters,Vo1.26,No.34,po …