The colorectal cancer microbiota alter their transcriptome to adapt to the acidity, reactive oxygen species, and metabolite availability of gut microenvironments

MTF Lamaudière, R Arasaradnam, GD Weedall… - Msphere, 2023 - Am Soc Microbiol
The gut microbiome is implicated in the pathology of colorectal cancer (CRC). However, the
mechanisms by which the microbiota actively contribute to disease onset and progression …

The colorectal cancer gut environment regulates activity of the microbiome and promotes the multidrug resistant phenotype of ESKAPE and other pathogens

MTF Lamaudière, R Arasaradnam, GD Weedall… - Msphere, 2023 - Am Soc Microbiol
Taxonomic composition of the gut microbiota in colorectal cancer (CRC) patients is altered,
a newly recognized driving force behind the disease, the activity of which has been …

Microbiome in colorectal cancer: how to get from meta-omics to mechanism?

D Ternes, J Karta, M Tsenkova, P Wilmes, S Haan… - Trends in …, 2020 - cell.com
Mounting evidence from metagenomic analyses suggests that a state of pathological
microbial imbalance or dysbiosis is prevalent in the gut of patients with colorectal cancer …

Towards the human colorectal cancer microbiome

JR Marchesi, BE Dutilh, N Hall, WHM Peters… - PloS one, 2011 - journals.plos.org
Multiple factors drive the progression from healthy mucosa towards sporadic colorectal
carcinomas and accumulating evidence associates intestinal bacteria with disease initiation …

[HTML][HTML] Microbiome and colorectal cancer: Roles in carcinogenesis and clinical potential

E Saus, S Iraola-Guzmán, JR Willis… - Molecular aspects of …, 2019 - Elsevier
The gastrointestinal tract harbors most of the microbiota associated with humans. In recent
years, there has been a surge of interest in assessing the relationships between the gut …

The role of the gut microbiome in colorectal cancer development and therapy response

L Sánchez-Alcoholado, B Ramos-Molina, A Otero… - Cancers, 2020 - mdpi.com
Colorectal cancer (CRC) is the third most common cancer worldwide and the leading cause
of cancer-related deaths. Recently, several studies have demonstrated that gut microbiota …

Gut microbiome in colorectal cancer: Clinical diagnosis and treatment

Y Liu, HCH Lau, WY Cheng, J Yu - Genomics, Proteomics & …, 2023 - academic.oup.com
Colorectal cancer (CRC) is one of the most frequently diagnosed cancers and the leading
cause of cancer-associated deaths. Epidemiological studies have shown that both genetic …

[HTML][HTML] The role of microbiota in gastrointestinal cancer and cancer treatment: chance or curse?

A Smet, J Kupcinskas, A Link, GL Hold… - Cellular and Molecular …, 2022 - Elsevier
The gastrointestinal (GI) tract is home to a complex and dynamic community of
microorganisms, comprising bacteria, archaea, viruses, yeast, and fungi. It is widely …

Colorectal cancer-associated microbiome patterns and signatures

L Zhao, WC Cho, MR Nicolls - Frontiers in Genetics, 2021 - frontiersin.org
The gut microbiome is dynamic and shaped by diet, age, geography, and environment. The
disruption of normal gut microbiota (dysbiosis) is closely related to colorectal cancer (CRC) …

Differential mucosal microbiome profiles across stages of human colorectal cancer

M Zhang, Y Lv, S Hou, Y Liu, Y Wang, X Wan - Life, 2021 - mdpi.com
Emerging evidences link gut microbiota to colorectal cancer (CRC) initiation and
development. However, the CRC stage-and spatial-specific bacterial taxa were less …