The role of toll‐like and protease‐activated receptors and associated intracellular signaling in Porphyromonas gingivalis‐infected gingival fibroblasts

E Palm, I Demirel, T Bengtsson, H Khalaf - Apmis, 2017 - Wiley Online Library
Porphyromonas gingivalis, which is considered a keystone agent in periodontitis, has
evolved elaborate mechanisms to grow and survive in a hostile milieu. The gingival …

The role of toll-like and protease-activated receptors in the expression of cytokines by gingival fibroblasts stimulated with the periodontal pathogen Porphyromonas …

E Palm, I Demirel, T Bengtsson, H Khalaf - Cytokine, 2015 - Elsevier
Porphyromonas gingivalis is a periodontitis-associated pathogen and interactions between
the bacterium and gingival fibroblasts play an important role in development and …

Pathogenesis of Important Virulence Factors of Porphyromonas gingivalis via Toll-Like Receptors

L Jia, N Han, J Du, L Guo, Z Luo, Y Liu - Frontiers in cellular and …, 2019 - frontiersin.org
Periodontitis is a common intraoral infection and is inextricably linked to systemic diseases.
Recently, the regulation between host immunologic response and periodontal pathogens …

[HTML][HTML] Proinflammatory signaling cascades of periodontopathic oral pathogen Porphyromonas gingivalis

BL Slomiany, A Slomiany - Journal of Biosciences and Medicines, 2018 - scirp.org
Porphyromonas gingivalis, is the most prominent member of the bacteria flora associated
with pathogenesis of periodontitis, a chronic inflammatory disease resulting in tooth loss …

Porphyromonas gingivalis lipopolysaccharide signaling in gingival fibroblasts–CD14 and Toll-like receptors

PL Wang, K Ohura - Critical Reviews in Oral Biology & …, 2002 - journals.sagepub.com
Periodontal disease is the major cause of adult tooth loss and is commonly characterized by
a chronic inflammation caused by infection of oral bacteria. Porphyromonas gingivalis (P …

Intracellular Signaling and Cytokine Induction upon Interactions of Porphyromonas gingivalis Fimbriae with Pattern‐Recognition Receptors

G Hajishengallis, H Sojar, RJ Genco… - Immunological …, 2004 - Taylor & Francis
Toll‐like receptors (TLRs) and other pattern‐recognition receptors (PRRs) of the innate
immune system form functional receptor complexes that recognize and respond to pathogen …

Identification of signaling pathways in macrophage exposed to Porphyromonas gingivalis or to its purified cell wall components

Q Zhou, S Amar - The Journal of Immunology, 2007 - journals.aai.org
Porphyromonas gingivalis (P. gingivalis) can trigger an inflammatory condition leading to the
destruction of periodontal tissues. However P. gingivalis LPS and its fimbriae (FimA) play …

PKC, ERK/p38 MAP kinases and NF‐κB targeted signalling play a role in the expression and release of IL‐1β and CXCL8 in Porphyromonas gingivalis‐infected …

K Jayaprakash, I Demirel, S Gunaltay, H Khalaf… - Apmis, 2017 - Wiley Online Library
Porphyromonas gingivalis is a keystone pathogen in periodontitis and is gaining importance
in cardiovascular pathogenesis. Protease‐activated receptors (PAR s), toll‐like receptors …

Interleukin-1β modulates proinflammatory cytokine production in human epithelial cells

MA Eskan, MR Benakanakere, BG Rose… - Infection and …, 2008 - Am Soc Microbiol
Periodontitis is a chronic human inflammatory disease initiated and sustained by dental
plaque microorganisms. A major contributing pathogen is Porphyromonas gingivalis, a gram …

TLR2 Activation by Porphyromonas gingivalis Requires Both PPAD Activity and Fimbriae

A Wielento, GP Bereta, KB Łagosz-Ćwik… - Frontiers in …, 2022 - frontiersin.org
Porphyromonas gingivalis, a keystone oral pathogen implicated in development and
progression of periodontitis, may also contribute to the pathogenicity of diseases such as …