[HTML][HTML] Interkingdom gene transfer of a hybrid NPS/PKS from bacteria to filamentous ascomycota
Nonribosomal peptides (NRPs) and polyketides (PKs) are ecologically important secondary
metabolites produced by bacteria and fungi using multidomain enzymes called …
metabolites produced by bacteria and fungi using multidomain enzymes called …
New PCR primers for the screening of NRPS and PKS-I systems in actinomycetes: detection and distribution of these biosynthetic gene sequences in major taxonomic …
A Ayuso-Sacido, O Genilloud - Microbial ecology, 2005 - Springer
Nonribosomal peptide synthetases (NRPS) and type I polyketide synthases (PKS-I) are
biosynthetic systems involved in the synthesis of a large number of important biologically …
biosynthetic systems involved in the synthesis of a large number of important biologically …
[HTML][HTML] Genus level analysis of PKS-NRPS and NRPS-PKS hybrids reveals their origin in Aspergilli
S Theobald, TC Vesth, MR Andersen - BMC genomics, 2019 - Springer
Background Filamentous fungi produce a vast amount of bioactive secondary metabolites
(SMs) synthesized by eg hybrid polyketide synthase-nonribosomal peptide synthetase …
(SMs) synthesized by eg hybrid polyketide synthase-nonribosomal peptide synthetase …
Discovery and Characterization of a PKS–NRPS Hybrid in Aspergillus terreus by Genome Mining
S Tang, W Zhang, Z Li, H Li, C Geng… - Journal of natural …, 2020 - ACS Publications
Fungal polyketide synthase–nonribosomal peptide synthetase (PKS–NRPS) hybrids have
been characterized to produce polyketide–amino acid compounds with striking structural …
been characterized to produce polyketide–amino acid compounds with striking structural …
[HTML][HTML] Endogenous cross-talk of fungal metabolites
Non-ribosomal peptide (NRP) synthesis in fungi requires a ready supply of proteogenic and
non-proteogenic amino acids which are subsequently incorporated into the nascent NRP via …
non-proteogenic amino acids which are subsequently incorporated into the nascent NRP via …
[HTML][HTML] Linker flexibility facilitates module exchange in fungal hybrid PKS-NRPS engineering
ML Nielsen, T Isbrandt, LM Petersen, UH Mortensen… - PLoS …, 2016 - journals.plos.org
Polyketide synthases (PKSs) and nonribosomal peptide synthetases (NRPSs) each give rise
to a vast array of complex bioactive molecules with further complexity added by the …
to a vast array of complex bioactive molecules with further complexity added by the …
[HTML][HTML] Biosynthesis of natural products by microbial iterative hybrid PKS–NRPS
KM Fisch - RSC advances, 2013 - pubs.rsc.org
Biosynthesis of natural products by microbial iterative hybrid PKS–NRPS - RSC Advances (RSC
Publishing) DOI:10.1039/C3RA42661K Royal Society of Chemistry View PDF VersionPrevious …
Publishing) DOI:10.1039/C3RA42661K Royal Society of Chemistry View PDF VersionPrevious …
Insect-specific polyketide synthases (PKSs), potential PKS-nonribosomal peptide synthetase hybrids, and novel PKS clades in tropical fungi
A Amnuaykanjanasin, S Phonghanpot… - Applied and …, 2009 - Am Soc Microbiol
Polyketides draw much attention because of their potential use in pharmaceutical and
biotechnological applications. This study identifies an abundant pool of polyketide synthase …
biotechnological applications. This study identifies an abundant pool of polyketide synthase …
Functional Analysis of All Nonribosomal Peptide Synthetases in Cochliobolus heterostrophus Reveals a Factor, NPS6, Involved in Virulence and Resistance to …
BN Lee, S Kroken, DYT Chou, B Robbertse… - Eukaryotic …, 2005 - Am Soc Microbiol
Nonribosomal peptides, made by nonribosomal peptide synthetases, have diverse
biological activities, including roles as fungal virulence effectors. Inspection of the genome of …
biological activities, including roles as fungal virulence effectors. Inspection of the genome of …
[HTML][HTML] The Mosaic Architecture of NRPS-PKS in the Arbuscular Mycorrhizal Fungus Gigaspora margarita Shows a Domain With Bacterial Signature
As obligate biotrophic symbionts, arbuscular mycorrhizal fungi (AMF) live in association with
most land plants. Among them, Gigaspora margarita has been deeply investigated because …
most land plants. Among them, Gigaspora margarita has been deeply investigated because …