Phytoestrogens have been investigated as natural alternatives to hormone replacement
therapy and their potential as chemopreventive agents. We investigated the effects of equol …

Phytoestrogens have attracted attention as being safer alternatives to hormone replacement
therapy (HRT) and as chemopreventive reagents for breast cancer because dietary soy …

Objective To explore the impact of lower concentrations of phytoestrogens on 17β-estradiol
(E2) in the growth of MCF-7 breast cells. Methods MCF-7 cells were treated with E2 (10− 8 …

Phytoestrogens derived from plants exert estrogenic as well as antiestrogenic effects and
multiple actions within breast cancer cells. Chemopreventive properties of phytoestrogens …

Administration of estrogen replacement therapy (ERT) decreases the incidence of breast
cancer, as shown in a double-blind, placebo-controlled randomized trial of the Women's …

Phytoestrogens have multiple actions within target cells, including the epigenome, which
could be beneficial to the development and progression of breast cancer. In this brief review …

In this study, we investigated the underlying mechanism by which phytoestrogens suppress
the growth of normal (MCF-10A) and malignant (MDA-MB-231) estrogen receptor α (ERα) …

Phytoestrogens have been described to be weak estrogens, SERMs or exhibit
antiestrogenic properties. However, information about their activity in presence of estrogens …

Objective To explore the effect and pathway of phytoestrogens in vitro on the growth of both
normal and malignant breast cells. Methods Normal breast MCF-10A cells and breast …

Aim To explore the ex vivo effects of phytoestrogens on primary human breast cancer cells.
Methods Breast cancer cells were obtained from patients who underwent primary breast …