Keypoints Numerous epilepsy genes have been identified in the last years, mostly in the
(rare) monogenic forms and thanks to the increased availability and the decreased cost of …

New approaches to gene discovery and characterization are advancing rapidly our
understanding of the genetic and phenotypic architecture of the epilepsies. This review …

In last few years there has been rapid increase in the knowledge of epilepsy genetics.
Nowadays, it is estimated that genetic epilepsies include over than 30% of all epilepsy …

Epilepsy encompasses a group of heterogeneous brain diseases that affect more than 50
million people worldwide. Epilepsy may have discernible structural, infectious, metabolic …

The rapid pace of disease gene discovery has resulted in tremendous advances in the field
of epilepsy genetics. Clinical testing with comprehensive gene panels, exomes, and …

Treatment strategies based on the molecular biology of the epilepsies may soon become a
reality. Critical steps in this process are identifying molecular genetic defects in specific …

The field of epilepsy genetics is contentious, particularly when it concerns the common
epilepsies. More than a dozen loci have been suggested, the result of either linkage …

While genetic causes of epilepsy have been hypothesized from the time of Hippocrates, the
advent of new genetic technologies has played a tremendous role in elucidating a growing …

Progress in understanding the genetics of epilepsy is proceeding at a dizzying pace. Due in
large part to rapid progress in molecular genetics, gene defects underlying many of the …

Abstract Development in genetic technology has led to the identification of an increasing
number of genes associated with epilepsy. These discoveries will both provide the basis for …