Synergistic interaction between total glucosides and total flavonoids on chronic constriction injury induced neuropathic pain in rats

J Zhang, C Lv, H Wang, Y Cao - Pharmaceutical Biology, 2013 - Taylor & Francis
Context: Shaoyao Gancao Decoction (SGD), a famous herbal medicine, consists of two
herbs (Paeoniae Radix and Glycyrrhizae Radix) and is traditionally used for the treatment of …

Serotonergically dependent antihyperalgesic and antiallodynic effects of isoliquiritin in a mouse model of neuropathic pain

C Yu, Y Zhang, KX Gao, HT Sun, MZ Gong… - European journal of …, 2020 - Elsevier
Chronic neuropathic pain poses a significant health problem worldwide, for which effective
treatment is lacking. The current work aimed to investigate the potential analgesic effect of …

Analgesic effect of total flavonoids from Sanguis draxonis on spared nerve injury rat model of neuropathic pain

FF Chen, FQ Huo, H Xiong, Q Wan, YN Zheng, WJ Du… - Phytomedicine, 2015 - Elsevier
Background Sanguis draxonis (SD) is a kind of red resin obtained from the wood of
Dracaena cochinchinensis (Lour.) SC Chen (D. cochinchinensis). The active components of …

Gastrodia elata Blume Polysaccharides Attenuate Vincristine‐Evoked Neuropathic Pain through the Inhibition of Neuroinflammation

H Xie, Y Chen, W Wu, X Feng… - Mediators of Inflammation, 2021 - Wiley Online Library
Vincristine (Vin) is a well‐known antitumor agent that frequently evokes neuropathic pain
and decreases the quality of life of patients. Polysaccharides (GBP) extracted from Gastrodia …

Tanshinone IIA attenuates diabetic peripheral neuropathic pain in experimental rats via inhibiting inflammation

B Zhang, Y Yu, G Aori, Q Wang, D Kong… - Evidence‐Based …, 2018 - Wiley Online Library
Diabetic peripheral neuropathic pain (DPNP) is a common and intractable complication of
diabetes. Conventional therapies are always not ideal; development of novel drugs is still …

Antinociceptive and anti-inflammatory effects of cryptotanshinone through PI3K/Akt signaling pathway in a rat model of neuropathic pain

W Zhang, M Suo, G Yu, M Zhang - Chemico-Biological Interactions, 2019 - Elsevier
Peripheral nerve injuries often induce neuropathic pain through inflammation.
Cryptotanshinone isolated from Salvia miltiorrhiza Bunge has been found to exert anti …

Ginsenoside R f relieves mechanical hypersensitivity, depression‐like behavior, and inflammatory reactions in chronic constriction injury rats

Y Li, C Chen, S Li, C Jiang - Phytotherapy Research, 2019 - Wiley Online Library
The aim of this study was to investigate whether ginsenoside Rf can effectively relieve pain
hypersensitivity in a neuropathic pain rat model. Neuropathic pain was induced in rats by …

(+)-Catechin Alleviates CCI-Induced Neuropathic Pain in Rats by Modulating the IL34/CSFIR Axis and Attenuating the Schwann Cell-Macrophage Cascade Response …

B Jing, Z Chen, W Si, J Zhao, G Zhao, D Zhang - Molecular Neurobiology, 2023 - Springer
The aim of this study was to investigate the potential therapeutic applications of (+)-catechin
in the treatment of neuropathic pain. In vivo study, 32 SD rats were randomly divided into …

Tetrahydroxystilbene glucoside relieves the chronic inflammatory pain by inhibiting neuronal apoptosis, microglia activation, and GluN2B overexpression in anterior …

Y Fan, S Guan, L Luo, Y Li, L Yang, X Zhou… - Molecular …, 2018 - journals.sagepub.com
Tetrahydroxystilbene glucoside (THSG) is one of the active ingredients of Polygonum
multiflorum. It has been shown to exert a variety of pharmacological effects, including …

Chondroitin and glucosamine sulphate reduced proinflammatory molecules in the DRG and improved axonal function of injured sciatic nerve of rats

OF Olaseinde, BV Owoyele - Scientific reports, 2022 - nature.com
Neuropathic pain (NP) is an abnormality resulting from lesion or damage to parts of the
somatosensory nervous system. It is linked to defective quality of life and often poorly …