Statins (HMG-CoA reductase inhibitors) are one of the most widely prescribed medications
in the world. However, their use in patients is often inappropriate because these medications …

Cardiovascular disease is the most common cause of death in the United States and
worldwide. Most of this disease is preventable with improvement of lifestyle and medication …

Controversy erupted last fall when new guidelines from the American Heart Association and
American College of Cardiology altered recommendations for cholesterol-lowering statin …

In randomized trials and meta-analyses, statins decrease myocardial infarction, stroke,
vascular death, and total mortality. 1 The totality of evidence indicates no threshold below …

HMG CoA reductase inhibitors (statins) promote reduction in plasma levels of Low Density
Lipoprotein (LDL) cholesterol, a primary risk factor in coronary artery disease. Numerous …

Reducing cholesterol levels saves lives. Statin drugs are effective ways of lowering
cholesterol levels. Several large-scale randomized controlled trials have demonstrated that …

on mortality and reduced coronary events only a modest 21% but increased abnormal liver
function 6-fold (4). Extrapolating from on mortality and reduced coronary events only a …

The underlying cause of heart disease is a process called atherosclerosis. Atherosclerosis
has been described simply as hardening of the arteries, but in truth, it involves a complex …

Although the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, or statins, share a
common lipid-lowering effect, there are differences within this class of drugs. The low …

Fuster 1 wrote in favor of a nonprescription statin program to provide patients with easier
access to a proved benefit in cardiovascular (CV) risk prevention. Dr. Fuster stated that there …