The altered entry pathway and antigenic distance of the SARS-CoV-2 Omicron variant map to separate domains of spike protein
TP Peacock, JC Brown, J Zhou, N Thakur, K Sukhova… - biorxiv, 2022 - biorxiv.org
At the end of 2021 a new SARS-CoV-2 variant, Omicron, emerged and quickly spread
across the world. It has been demonstrated that Omicron's high number of Spike mutations …
across the world. It has been demonstrated that Omicron's high number of Spike mutations …
[PDF][PDF] The SARS-CoV-2 variant, Omicron, shows rapid replication in human primary nasal epithelial cultures and efficiently uses the endosomal route of entry
TP Peacock, JC Brown, J Zhou, N Thakur… - …, 2022 - pdfs.semanticscholar.org
At the end of 2021 a new SARS-CoV-2 variant, Omicron, emerged and quickly spread
across the world. It has been demonstrated that Omicron's high number of Spike mutations …
across the world. It has been demonstrated that Omicron's high number of Spike mutations …
SARS-CoV-2 Omicron spike mediated immune escape and tropism shift
B Meng, IATM Ferreira, A Abdullahi, N Goonawardane… - BioRxiv, 2021 - biorxiv.org
Abstract The SARS-CoV-2 Omicron BA. 1 variant emerged in late 2021 and is characterised
by multiple spike mutations across all spike domains. Here we show that Omicron BA. 1 has …
by multiple spike mutations across all spike domains. Here we show that Omicron BA. 1 has …
[HTML][HTML] SARS-CoV-2 Omicron spike mediated immune escape and tropism shift
R Gupta - Research square, 2022 - ncbi.nlm.nih.gov
Abstract The SARS-CoV-2 Omicron BA. 1 variant emerged in late 2021 and is characterised
by multiple spike mutations across all spike domains. Here we show that Omicron BA. 1 has …
by multiple spike mutations across all spike domains. Here we show that Omicron BA. 1 has …
SARS-CoV-2 Omicron spike H655Y mutation is responsible for enhancement of the endosomal entry pathway and reduction of cell surface entry pathways
M Yamamoto, K Tomita, Y Hirayama, J Inoue… - BioRxiv, 2022 - biorxiv.org
Abstract The SARS-CoV-2 Omicron variant reportedly displays decreased usage of the cell
surface entry pathway mediated by the host transmembrane protease, serine 2 (TMPRSS2) …
surface entry pathway mediated by the host transmembrane protease, serine 2 (TMPRSS2) …
[HTML][HTML] Omicron: Master of immune evasion maintains robust ACE2 binding
M Hoffmann, L Zhang, S Pöhlmann - Signal Transduction and Targeted …, 2022 - nature.com
The spike (S) protein of the SARS-CoV-2 Omicron variant is highly mutated but the impact of
these mutations on viral entry into cells and its inhibition by antibodies has been unclear. A …
these mutations on viral entry into cells and its inhibition by antibodies has been unclear. A …
The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism
Vaccination-based exposure to spike protein derived from early SARS-CoV-2 sequences is
the key public health strategy against COVID-19. Successive waves of SARS-CoV-2 …
the key public health strategy against COVID-19. Successive waves of SARS-CoV-2 …
SARS-CoV-2 Omicron efficiently infects human airway, but not alveolar epithelium
MM Lamers, AZ Mykytyn, TI Breugem, N Groen… - BioRxiv, 2022 - biorxiv.org
In late 2021, the highly mutated SARS-CoV-2 Omicron variant emerged, raising concerns
about its potential extensive immune evasion, increased transmissibility and pathogenicity …
about its potential extensive immune evasion, increased transmissibility and pathogenicity …
[HTML][HTML] SARS-CoV-2 Omicron strain exhibits potent capabilities for immune evasion and viral entrance
X Zhang, S Wu, B Wu, Q Yang, A Chen, Y Li… - Signal transduction and …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron strain (as known
as B. 1.1. 529) was identified in Botswana and South Africa in early November 2021 and …
as B. 1.1. 529) was identified in Botswana and South Africa in early November 2021 and …
Spike mutations contributing to the altered entry preference of SARS-CoV-2 omicron BA. 1 and BA. 2
ABSTRACT SARS-CoV-2 B. 1.1. 529.1 (Omicron BA. 1) emerged in November 2021 and
quickly became the predominant circulating SARS-CoV-2 variant globally. Omicron BA. 1 …
quickly became the predominant circulating SARS-CoV-2 variant globally. Omicron BA. 1 …