Ventilation-perfusion (V̇a/Q̇) mismatch during exercise may result from interstitial
pulmonary edema if increased pulmonary vascular pressure causes fluid efflux into the …

Heavy exercise increases ventilation-perfusion mismatch and decreases pulmonary gas
exchange efficiency. Previous work using magnetic resonance imaging (MRI) arterial spin …

During maximal exercise, ventilation-perfusion inequality increases, especially in athletes.
The mechanism remains speculative. We hypothesized that, if interstitial pulmonary edema …

The purpose of this study was to examine the effects of exercise on extravascular lung water
as it may relate to pulmonary gas exchange. Ten male humans underwent measures of …

We do not think there is much debate to this opinion piece. Several studies using healthy
human subjects (2, 4, 5, 7) demonstrate evidence of pulmonary edema from sea-level …

Exercise presents a considerable stress to the pulmonary system and ventilation-perfusion
(V̇a/Q̇) heterogeneity increases with exercise, affecting the efficiency of gas exchange. In …

Prone posture increases cardiac output and improves pulmonary gas exchange. We
hypothesized that, in the supine posture, greater compression of dependent lung limits …

Ventilation-perfusion (VA/Q) mismatch has been shown to increase during exercise,
especially in hypoxia. A possible explanation is subclinical interstitial edema due to high …

TO THE EDITOR: I would like to thank my colleagues and all who contributed their thoughts
to this interesting debate. As Dr. Eldridge (see Ref. 7) suggests, to address these questions …

To determine whether intense, prolonged activity can induce transient pulmonary edema,
eight highly trained male cyclists (mean±SD: age, 26.9±3.0 years; height, 179.9±5.7 cm; …