[HTML][HTML] Genome mining reveals novel biosynthetic gene clusters in entomopathogenic bacteria
W Meesil, P Muangpat, S Sitthisak, T Rattanarojpong… - Scientific Reports, 2023 - nature.com
The discovery of novel bioactive compounds produced by microorganisms holds significant
potential for the development of therapeutics and agrochemicals. In this study, we conducted …
potential for the development of therapeutics and agrochemicals. In this study, we conducted …
[HTML][HTML] Genome analysis of secondary metabolite‑biosynthetic gene clusters of Photorhabdus akhurstii subsp. akhurstii and its antibacterial activity against antibiotic …
P Muangpat, W Meesil, J Ngoenkam, Y Teethaisong… - Plos one, 2022 - journals.plos.org
Xenorhabdus and Photorhabdus can produce a variety of secondary metabolites with broad
spectrum bioactivity against microorganisms. We investigated the antibacterial activity of …
spectrum bioactivity against microorganisms. We investigated the antibacterial activity of …
[HTML][HTML] Mining Biosynthetic Gene Clusters of Pseudomonas vancouverensis Utilizing Whole Genome Sequencing
P Tamang, A Upadhaya, P Paudel, K Meepagala… - Microorganisms, 2024 - mdpi.com
Natural product (NP)-based pesticides have emerged as a compelling alternative to
traditional chemical fungicides, attracting substantial attention within the agrochemical …
traditional chemical fungicides, attracting substantial attention within the agrochemical …
Natural product discovery through microbial genome mining
The advent of the genomic era has opened up enormous possibilities for the discovery of
new natural products. Also known as specialized metabolites, these compounds produced …
new natural products. Also known as specialized metabolites, these compounds produced …
Comprehensive curation and analysis of fungal biosynthetic gene clusters of published natural products
YF Li, KJS Tsai, CJB Harvey, JJ Li, BE Ary… - Fungal Genetics and …, 2016 - Elsevier
Microorganisms produce a wide range of natural products (NPs) with clinically and
agriculturally relevant biological activities. In bacteria and fungi, genes encoding successive …
agriculturally relevant biological activities. In bacteria and fungi, genes encoding successive …
[HTML][HTML] High-Throughput Mining of Novel Compounds from Known Microbes: A Boost to Natural Product Screening
Advanced techniques can accelerate the pace of natural product discovery from microbes,
which has been lagging behind the drug discovery era. Therefore, the present review article …
which has been lagging behind the drug discovery era. Therefore, the present review article …
Genome-based bioprospecting of microbes for new therapeutics
SB Zotchev, ON Sekurova, L Katz - Current opinion in biotechnology, 2012 - Elsevier
Bioprospecting of natural sources for new medicines has a long and successful history,
exemplified by the fact that over 50% of all drugs currently on the market are either derived …
exemplified by the fact that over 50% of all drugs currently on the market are either derived …
[HTML][HTML] Detecting and prioritizing biosynthetic gene clusters for bioactive compounds in bacteria and fungi
Secondary metabolites (SM) produced by fungi and bacteria have long been of exceptional
interest owing to their unique biomedical ramifications. The traditional discovery of new …
interest owing to their unique biomedical ramifications. The traditional discovery of new …
Microbial genome mining for accelerated natural products discovery: is a renaissance in the making?
BO Bachmann, SG Van Lanen… - Journal of industrial …, 2014 - academic.oup.com
Microbial genome mining is a rapidly developing approach to discover new and novel
secondary metabolites for drug discovery. Many advances have been made in the past …
secondary metabolites for drug discovery. Many advances have been made in the past …
New keys to unlock the treasure trove of microbial natural products
New keys to unlock the treasure trove of microbial natural products | Nature Reviews Microbiology
Skip to main content Thank you for visiting nature.com. You are using a browser version with …
Skip to main content Thank you for visiting nature.com. You are using a browser version with …