Production of bioactive plant secondary metabolites through in vitro technologies—status and outlook

C Wawrosch, SB Zotchev - Applied Microbiology and Biotechnology, 2021 - Springer
Medicinal plants have been used by mankind since ancient times, and many bioactive plant
secondary metabolites are applied nowadays both directly as drugs, and as raw materials …

Biotechnological production of pharmaceuticals and biopharmaceuticals in plant cell and organ cultures

D Hidalgo, R Sanchez, L Lalaleo… - Current medicinal …, 2018 - ingentaconnect.com
Background: Plant biofactories are biotechnological platforms based on plant cell and organ
cultures used for the production of pharmaceuticals and biopharmaceuticals, although to …

Bioreactor technology: A novel industrial tool for high‐tech production of bioactive molecules and biopharmaceuticals from plant roots

G Sivakumar - Biotechnology Journal: Healthcare Nutrition …, 2006 - Wiley Online Library
Plants are the richest source for different bioactive molecules. Because of the vast number of
side effects associated with synthetic pharmaceuticals, medical biotechnologists turned to …

Changing trends in biotechnology of secondary metabolism in medicinal and aromatic plants

SG Gandhi, V Mahajan, YS Bedi - Planta, 2015 - Springer
Main conclusion Medicinal and aromatic plants are known to produce secondary
metabolites that find uses as flavoring agents, fragrances, insecticides, dyes and drugs …

Secondary metabolism of pharmaceuticals in the plant in vitro cultures: strategies, approaches, and limitations to achieving higher yield

T Isah, S Umar, A Mujib, MP Sharma… - Plant Cell, Tissue and …, 2018 - Springer
Biotechnology is playing a vital alternative role in the production of pharmaceutical plant
secondary metabolites to support industrial production and mitigate over-exploitation of …

Production of secondary metabolites using tissue culture-based biotechnological applications

II Ozyigit, I Dogan, A Hocaoglu-Ozyigit… - Frontiers in Plant …, 2023 - frontiersin.org
Plants are the sources of many bioactive secondary metabolites which are present in plant
organs including leaves, stems, roots, and flowers. Although they provide advantages to the …

Current approaches toward production of secondary plant metabolites

MS Hussain, S Fareed, S Ansari… - Journal of Pharmacy …, 2012 - journals.lww.com
Plants are the tremendous source for the discovery of new products with medicinal
importance in drug development. Today several distinct chemicals derived from plants are …

[PDF][PDF] Advancements in the production of secondary metabolites

V Varma - Journal of Natural Products, 2010 - researchgate.net
Plant cell culture systems represent a potential renewable source of valuable medicinal
compounds, flavours, fragrances, and colorants, which cannot be produced by microbial …

Genetic manipulation and bioreactor culture of plants as a tool for industry and its applications

T Kowalczyk, A Merecz-Sadowska, L Picot… - Molecules, 2022 - mdpi.com
In recent years, there has been a considerable increase in interest in the use of transgenic
plants as sources of valuable secondary metabolites or recombinant proteins. This has been …

In vitro plant tissue culture: means for production of biological active compounds

CA Espinosa-Leal, CA Puente-Garza, S García-Lara - Planta, 2018 - Springer
Main conclusion Plant tissue culture as an important tool for the continuous production of
active compounds including secondary metabolites and engineered molecules. Novel …