The role of interleukin-18 in the development and progression of atherosclerosis

A Bahrami, T Sathyapalan… - Current Medicinal …, 2021 - ingentaconnect.com
Atherosclerosis (AS), as a chronic inflammatory disorder of the cardiovascular system, is one
of the leading causes of ischemic heart disease, stroke and peripheral vascular disease …

[PDF][PDF] Role of IL-18 and its signaling in atherosclerosis

O Bhat, V Dhawan - Inflammation and cell Signaling, 2015 - researchgate.net
Cardiovascular diseases (CVD) including coronary artery disease (CAD) and stroke are the
largest cause of worldwide morbidity and mortality, where atherosclerosis is the underlying …

[HTML][HTML] The pleiotropic role of interleukin-17 in atherosclerosis

G Allam, A Abdel-Moneim, AM Gaber - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Atherosclerosis is the main cause of cardiovascular diseases (CVDs), which considers the
leading cause of mortality worldwide. Atherosclerosis is a chronic inflammatory condition of …

Proatherogenic role of interleukin-18: effects on inflammation and action on vascular cells: AUTHORS'RETROSPECTIVE

R Elhage, HG Ljunggren… - Cardiovascular research, 2012 - academic.oup.com
Today, multiple different pieces of evidence set inflammation as a key pathogenetic
mechanism in the development of atherosclerosis and its complications. 1–4 A better …

Expression of interleukin-18 in human atherosclerotic plaques and relation to plaque instability

Z Mallat, A Corbaz, A Scoazec, S Besnard, G Lesèche… - Circulation, 2001 - Am Heart Assoc
Background Interleukin (IL)-18 is a potent proinflammatory cytokine with potential
atherogenic properties. Its expression and role in atherosclerosis, however, are unknown …

The two faces of interleukin-17A in atherosclerosis

M Akhavanpoor, H Akhavanpoor… - Current Drug …, 2017 - ingentaconnect.com
A complex network of different cytokines and chemokines modulates atherosclerosis, a
chronic inflammatory disease. Interleukin-17A (IL-17A) is expressed by different leukocyte …

Interleukin-17 and acute coronary syndrome

S Su, H Ma, L Shen, M Xiang, J Wang - Journal of Zhejiang University …, 2013 - Springer
Inflammation plays an important role in atherosclerosis, which is also crucial for acute
coronary syndrome (ACS). Recent studies have revealed that interleukin (IL)-17, which was …

Interleukin-18/interleukin-18 binding protein signaling modulates atherosclerotic lesion development and stability

Z Mallat, A Corbaz, A Scoazec, P Graber… - Circulation …, 2001 - Am Heart Assoc
Interleukin (IL)-18 is the interferon-γ–inducing factor and has other proinflammatory
properties. The precise role of IL-18 in immunoinflammatory diseases remains poorly …

Interleukin-18 Enhances Atherosclerosis in Apolipoprotein E−/− Mice Through Release of Interferon-γ

SC Whitman, P Ravisankar, A Daugherty - Circulation research, 2002 - Am Heart Assoc
We have previously shown that interferon-γ (IFN-γ) is a potent enhancer of atherogenesis.
Interleukin-18 (IL-18) promotes inflammatory responses through release of IFN-γ, although it …

Role of interleukin-10 in atherogenesis and plaque stabilization

B Halvorsen, T Waehre, H Scholz, JK Damås… - Future …, 2006 - Taylor & Francis
Considerable progress has been made in the understanding of atherogenesis and
atherosclerosis is now considered to be an inflammatory disease of the vessel wall involving …