[PDF][PDF] Novel Digital Pathology quantitative image analysis and AI method detects traits of fibrosis treatment response

L Chen, A Minnich, V Baxi, ED Charles, ZD Goodman… - Hepatology, 2023 - fibronest.com
METHOD RESULTS BACKGROUND and AIMS Conclusion DIGITAL PATHOLOGY METHOD
References Histological Traits of Treatment Response Page 1 Novel Digital Pathology …

Inflammation and fibrosis in Crohn's disease: location-matched histological correlation of small bowel ultrasound features

G Bhatnagar, M Rodriguez-Justo, A Higginson… - Abdominal …, 2021 - Springer
Purpose To evaluate the utility of mural and extramural sonographic features of Crohn's
Disease as potential imaging biomarkers of inflammation and fibrosis against whole-mount …

Ultrasound shear wave elastography in pediatric stricturing small bowel Crohn disease: correlation with histology and second harmonic imaging microscopy

N Abu-Ata, JR Dillman, JM Rubin, MH Collins… - Pediatric …, 2023 - Springer
Background Preclinical animal as well as small exploratory ex vivo and in vivo human
studies have suggested that bowel wall shear wave speed (SWS) measurements may be a …

The heterogeneous morphology of networked collagen in distal colon and rectum of mice quantified via nonlinear microscopy

F Maier, S Siri, S Santos, L Chen, B Feng… - Journal of the mechanical …, 2021 - Elsevier
Visceral pain from the distal colon and rectum (colorectum) is a major complaint of patients
with irritable bowel syndrome. Mechanotransduction of colorectal distension/stretch appears …

Role of ultra‐high definition endoscopy (endomicroscopy and endocytoscopy) and real‐time histologic examination in inflammatory bowel disease: Scoping review

P Pal, M Ramchandani, R Patel, R Banerjee… - Digestive …, 2024 - Wiley Online Library
Objectives Confocal laser endomicroscopy (CLE) and endocytoscopy (EC) are ultra‐high
definition (HD) imaging modalities that enable real‐time histological assessment. Although …

Smooth muscle hyperplasia/hypertrophy is the most prominent histological change in Crohn's fibrostenosing bowel strictures: a semiquantitative analysis by using a …

W Chen, C Lu, C Hirota, M Iacucci… - Journal of Crohn's …, 2017 - academic.oup.com
Background: The simplistically and ambiguously termed 'fibrostenosis' of bowel is a hallmark
of severe Crohn's disease [CD] and a major contributor to medical treatment failure. Non …

[HTML][HTML] Identifying the inflammatory and fibrotic bowel stricture: MRI diffusion-weighted imaging in Crohn's disease

J Zhu, F Zhang, F Liu, W He, J Tian, H Han… - Radiology of Infectious …, 2015 - Elsevier
Purpose To identify inflammatory and fibrotic mural stricture in Crohn's disease (CD) using
MR diffusion-weighted imaging (DWI) and to compare DWI findings with those of …

Assessment of ultra-early-stage liver fibrosis in human non-alcoholic fatty liver disease by second-harmonic generation microscopy

T Minamikawa, E Hase, M Ichimura-Shimizu… - International Journal of …, 2022 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is associated with the chronic progression of
fibrosis. In general, the progression of liver fibrosis is determined by a histopathological …

Evaluating bowel wall vascularity in Crohn's disease: a comparison of dynamic MRI and wideband harmonic imaging contrast-enhanced low MI ultrasound

S Pauls, A Gabelmann, SA Schmidt, A Rieber… - European …, 2006 - Springer
This was a prospective comparison of dynamic MRI (1.5 T) and echo-signal enhanced
ultrasound in evaluating vascularization in thickened bowel walls cases of Crohn's disease …

Measurement of liver stiffness using atomic force microscopy coupled with polarization microscopy

S Ojha, J Pribyl, S Klimovic, D Hadraba… - JoVE (Journal of …, 2022 - jove.com
Matrix stiffening has been recognized as one of the key drivers of the progression of liver
fibrosis. It has profound effects on various aspects of cell behavior such as cell function …