[HTML][HTML] Stimulation of appetite by ghrelin is regulated by leptin restraint: peripheral and central sites of action
SP Kalra, N Ueno, PS Kalra - The Journal of nutrition, 2005 - Elsevier
ABSTRACT A reciprocal rhythmic pattern of 2 afferent hormonal signals, anorexigenic leptin
and orexigenic ghrelin, imparts rhythmicity to the neuropeptide Y (NPY) system, the final …
and orexigenic ghrelin, imparts rhythmicity to the neuropeptide Y (NPY) system, the final …
Acute and chronic suppression of the central ghrelin signaling system reveals a role in food anticipatory activity
LAW Verhagen, E Egecioglu, MCM Luijendijk… - European …, 2011 - Elsevier
Using the rodent activity-based anorexia (ABA) model that mimics clinical features of
anorexia nervosa that include food restriction-induced hyperlocomotion, we found that …
anorexia nervosa that include food restriction-induced hyperlocomotion, we found that …
Overeating of palatable food is associated with blunted leptin and ghrelin responses
A Lindqvist, CD de la Cour, A Stegmark, R Håkanson… - Regulatory peptides, 2005 - Elsevier
Palatable food is rich in fat and/or sucrose. In this study we examined the long-term effects of
such diets on food intake, body weight, adiposity and circulating levels of the satiety peptide …
such diets on food intake, body weight, adiposity and circulating levels of the satiety peptide …
Leptin-induced downregulation of the rat hippocampal somatostatinergic system may potentiate its anorexigenic effects
A Perianes-Cachero, E Burgos-Ramos… - Neurochemistry …, 2012 - Elsevier
The learning and memory mechanisms in the hippocampus translate hormonal signals of
energy balance into behavioral outcomes involved in the regulation of food intake. As leptin …
energy balance into behavioral outcomes involved in the regulation of food intake. As leptin …
Leptin deficiency induced by fasting impairs the satiety response to cholecystokinin
JE McMinn, DK Sindelar, PJ Havel… - Endocrinology, 2000 - academic.oup.com
Leptin administration potentiates the satiety response to signals such as cholecystokinin
(CCK), that are released from the gut during a meal. To investigate the physiological …
(CCK), that are released from the gut during a meal. To investigate the physiological …
Effect of food availability and leptin on the physiology and hypothalamic gene expression of the golden spiny mouse: a desert rodent that does not hoard food
R Gutman, R Hacmon-Keren… - American Journal …, 2008 - journals.physiology.org
Food availability and quality in desert habitats are spatially and temporally unpredictable,
and animals face periods of food shortage. The golden spiny mouse (Acomys russatus) is an …
and animals face periods of food shortage. The golden spiny mouse (Acomys russatus) is an …
Ghrelin and orexin interact to increase meal size through a descending hippocampus to hindbrain signaling pathway
Background Memory and cognitive processes influence the amount of food consumed
during a meal, yet the neurobiological mechanisms mediating these effects are poorly …
during a meal, yet the neurobiological mechanisms mediating these effects are poorly …
Maintenance on a high-fat diet impairs the anorexic response to glucagon-like-peptide-1 receptor activation
DL Williams, N Hyvarinen, N Lilly, K Kay, A Dossat… - Physiology & …, 2011 - Elsevier
Previous data suggests that the adiposity signal leptin reduces food intake in part by
enhancing sensitivity to short-term signals that promote meal termination, including …
enhancing sensitivity to short-term signals that promote meal termination, including …
Presynaptic regulation of leptin in a defined lateral hypothalamus–ventral tegmental area neurocircuitry depends on energy state
Synaptic transmission controls brain activity and behaviors, including food intake. Leptin, an
adipocyte-derived hormone, acts on neurons located in the lateral hypothalamic area (LHA) …
adipocyte-derived hormone, acts on neurons located in the lateral hypothalamic area (LHA) …
The need to feed: homeostatic and hedonic control of eating
Feeding provides substrate for energy metabolism, which is vital to the survival of every
living animal and therefore is subject to intense regulation by brain homeostatic and hedonic …
living animal and therefore is subject to intense regulation by brain homeostatic and hedonic …