The learning and memory mechanisms in the hippocampus translate hormonal signals of
energy balance into behavioral outcomes involved in the regulation of food intake. As leptin …

Background Memory and cognitive processes influence the amount of food consumed
during a meal, yet the neurobiological mechanisms mediating these effects are poorly …

It is well established that leptin regulates energy balance largely through isoform B leptin
receptor-expressing neurons (LepR neurons) in the brain and that leptin activates one …

Weight regain frequently follows interventions that reduce body weight, leading to a failure in
long-term obesity treatment. Inhibitory proteins of the leptin signaling pathway, such as the …

Diet-induced obesity (DIO) in rodents is characterized by impaired activation of s ignal-t
ransducer and a ctivator of t ranscription 3 (STAT3) by leptin receptors (LepRb) within the …

After a period of forced overfeeding, many individuals actively compensate for this weight
gain by reducing food intake and maintaining this state of hypophagia well into the post …

Galanin-like peptide (GALP) is a newly discovered 60 amino acid peptide from the porcine
hypothalamus. GALP has been shown to be expressed predominantly in the arcuate …

Leptin and somatostatin (SRIF) have opposite effects on food seeking and ingestive
behaviors, functions partially regulated by the frontoparietal cortex and hippocampus …

Mammals respond to reduced food availability by becoming more wakeful and active, yet the
central pathways regulating arousal and instinctual motor programs (such as food seeking) …

Many animals hoard food, including humans, but despite its pervasiveness, little is known
about the physiological mechanisms underlying this appetitive behavior. We summarize …