Triple therapy in COPD: what we know and what we don't

PMA Calverley, H Magnussen… - COPD: Journal of …, 2017 - Taylor & Francis
Triple inhaled therapy for chronic obstructive pulmonary disease (COPD) consists of an
inhaled corticosteroid (ICS), a long-acting β2-agonist (LABA) and a long-acting muscarinic …

Triple therapy trials in COPD: a precision medicine opportunity

S Suissa, A Ariel - European Respiratory Journal, 2018 - Eur Respiratory Soc
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) strategy document for the
treatment of chronic obstructive pulmonary disease (COPD) suggests that, after …

Current appraisal of single inhaler triple therapy in COPD

B Lipworth, CRW Kuo, S Jabbal - International Journal of Chronic …, 2018 - Taylor & Francis
A single inhaler containing inhaled corticosteroid (ICS)/long-acting beta-agonist (LABA)/long-
acting muscarinic antagonist (LAMA) is a more convenient way of delivering triple therapy in …

Triple inhaler versus dual bronchodilator therapy in COPD: real-world effectiveness on mortality

S Suissa, S Dell'Aniello, P Ernst - COPD: Journal of Chronic …, 2022 - Taylor & Francis
Randomized trials of triple therapy including an inhaled corticosteroid (ICS) for chronic
obstructive pulmonary disease (COPD) reported remarkable benefits on mortality compared …

Triple versus dual inhaler therapy in moderate‐to‐severe COPD: A systematic review and meta‐analysis of randomized controlled trials

Y Zayed, M Barbarawi, B Kheiri… - The clinical …, 2019 - Wiley Online Library
Introduction Treatment of chronic obstructive pulmonary disease (COPD) is evolving
specially with triple inhaler therapy. Objectives To perform a meta‐analysis to ascertain the …

Impact of switching from triple therapy to dual bronchodilation in COPD: the DACCORD 'real world'study

CF Vogelmeier, H Worth, R Buhl, CP Criée… - Respiratory …, 2022 - Springer
Introduction Chronic obstructive pulmonary disease (COPD) guidelines recommend
reserving triple therapy of inhaled corticosteroid (ICS), long-acting β2-agonist (LABA) and …

Single-inhaler triple therapy in symptomatic COPD patients: FULFIL subgroup analyses

DMG Halpin, R Birk, N Brealey, GJ Criner… - ERJ open …, 2018 - Eur Respiratory Soc
Triple inhaled corticosteroid (ICS)/long-acting muscarinic antagonist (LAMA)/long-acting β2-
agonist (LABA) therapy is recommended for symptomatic patients with chronic obstructive …

Triple therapy versus single and dual long-acting bronchodilator therapy in COPD: a systematic review and meta-analysis

M Cazzola, P Rogliani, L Calzetta… - European Respiratory …, 2018 - Eur Respiratory Soc
We performed a meta-analysis to compare the impact of triple combination therapy with
inhaled corticosteroids (ICS), long-acting β2-agonists (LABAs) and long-acting muscarinic …

Initiation of triple therapy with multiple inhalers in chronic obstructive pulmonary disease: an analysis of treatment patterns from a US retrospective database study

DC Lane, S Stemkowski, RH Stanford, Z Tao - Journal of Managed Care & …, 2018 - jmcp.org
BACKGROUND: Evidence suggests that real-world treatment patterns of chronic obstructive
pulmonary disease (COPD) do not always follow evidence-based treatment …

The effects of single inhaler triple therapy vs single inhaler dual therapy or separate triple therapy for the management of chronic obstructive pulmonary disease: a …

CC Lai, CH Chen, CYH Lin, CY Wang… - International journal of …, 2019 - Taylor & Francis
Background This study aims to compare the effects of single inhaler triple therapy comprised
of inhaled corticosteroids (ICSs), long-acting β2-agonists (LABAs), and long-acting …