White matter microstructure in chronic moderate‐to‐severe traumatic brain injury: Impact of acute‐phase injury‐related variables and associations with outcome …

AK Håberg, A Olsen, KG Moen… - Journal of …, 2015 - Wiley Online Library
This study examines how injury mechanisms and early neuroimaging and clinical measures
impact white matter (WM) fractional anisotropy (FA), mean diffusivity (MD), and tract volumes …

Alterations in microstructure and local fiber orientation of white matter are associated with outcome after mild traumatic brain injury

M Mohammadian, T Roine, J Hirvonen… - Journal of …, 2020 - liebertpub.com
Mild traumatic brain injury (mTBI) can have long-lasting consequences. We investigated
white matter (WM) alterations at 6–12 months following mTBI using diffusion tensor imaging …

White matter integrity following traumatic brain injury: the association with severity of injury and cognitive functioning

G Spitz, JJ Maller, R O'Sullivan, JL Ponsford - Brain topography, 2013 - Springer
Traumatic brain injury (TBI) frequently results in impairments of memory, speed of
information processing, and executive functions that may persist over many years. Diffuse …

Investigating white matter tract microstructural changes at six–twelve weeks following mild traumatic brain injury: a combined diffusion tensor imaging and neurite …

LE Oehr, JYM Yang, J Chen, JJ Maller… - Journal of …, 2021 - liebertpub.com
Using diffusion-weighted imaging (DWI), research has demonstrated changes suggestive of
damage to white matter tracts (WMT) following mild traumatic brain injury (mTBI). Yet due to …

Diffusion tensor imaging reveals elevated diffusivity of white matter microstructure that is independently associated with long-term outcome after mild traumatic brain …

EM Palacios, EL Yuh, CL Mac Donald… - Journal of …, 2022 - liebertpub.com
Diffusion tensor imaging (DTI) literature on single-center studies contains conflicting results
regarding acute effects of mild traumatic brain injury (mTBI) on white matter (WM) …

White matter damage and cognitive impairment after traumatic brain injury

KM Kinnunen, R Greenwood, JH Powell, R Leech… - Brain, 2011 - academic.oup.com
White matter disruption is an important determinant of cognitive impairment after brain injury,
but conventional neuroimaging underestimates its extent. In contrast, diffusion tensor …

The evolution of white matter microstructural changes after mild traumatic brain injury: a longitudinal DTI and NODDI study

EM Palacios, JP Owen, EL Yuh, MB Wang… - Science …, 2020 - science.org
Neuroimaging biomarkers that can detect white matter (WM) pathology after mild traumatic
brain injury (mTBI) and predict long-term outcome are needed to improve care and develop …

Longitudinal white matter changes after traumatic axonal injury

AM Perez, J Adler, N Kulkarni, JF Strain… - Journal of …, 2014 - liebertpub.com
Diffusion tensor imaging (DTI) has been useful in showing compromise after traumatic
axonal injury (TAI) at the chronic stage; however, white matter (WM) compromise from acute …

Serial changes in the white matter diffusion tensor imaging metrics in moderate traumatic brain injury and correlation with neuro-cognitive function

R Kumar, M Husain, RK Gupta, KM Hasan… - Journal of …, 2009 - liebertpub.com
Diffuse axonal injury (DAI) that follows traumatic brain injury (TBI) is thought to be a major
contributor to neurocognitive dysfunction that sometimes follows TBI. Conventional magnetic …

Global white matter analysis of diffusion tensor images is predictive of injury severity in traumatic brain injury

RR Benson, SA Meda, S Vasudevan, Z Kou… - Journal of …, 2007 - liebertpub.com
Conventional clinical neuroimaging is insensitive to axonal injury in traumatic brain injury
(TBI). Immunocytochemical staining reveals changes to axonal morphology within hours …