[HTML][HTML] Urban particulate matter triggers lung inflammation via the ROS-MAPK-NF-κB signaling pathway

J Wang, J Huang, L Wang, C Chen, D Yang… - Journal of thoracic …, 2017 - ncbi.nlm.nih.gov
Background Particulate matter (PM) is a high risk factor for various respiratory diseases and
triggers an inflammatory response in lung tissues. However, the molecular mechanism of the …

Particulate matter (PM10) induces in vitro activation of human neutrophils, and lung histopathological alterations in a mouse model

A Valderrama, P Ortiz-Hernández, JM Agraz-Cibrián… - Scientific reports, 2022 - nature.com
The epidemiological association between exposure to particulate matter (PM10) and various
respiratory and cardiovascular problems is well known, but the mechanisms driving these …

Pulmonary inflammation induced by low-dose particulate matter exposure in mice

YL Chan, B Wang, H Chen, KF Ho… - … of Physiology-Lung …, 2019 - journals.physiology.org
Air pollution is a ubiquitous problem and comprises gaseous and particulate matter (PM).
Epidemiological studies have clearly shown that exposure to PM is associated with impaired …

PM2. 5‐induced pulmonary inflammation via activating of the NLRP3/caspase‐1 signaling pathway

H Jia, Y Liu, D Guo, W He, L Zhao… - Environmental …, 2021 - Wiley Online Library
Abstract Particulate matter 2.5 (PM2. 5)‐induced pulmonary inflammation has become a
public concern in recent years. In which, the activation of the NLRP3/caspase‐1 pathway …

PM2.5-induced oxidative stress increases intercellular adhesion molecule-1 expression in lung epithelial cells through the IL-6/AKT/STAT3/NF-κB-dependent …

CW Liu, TL Lee, YC Chen, CJ Liang, SH Wang… - Particle and fibre …, 2018 - Springer
Background Epidemiological studies have shown that ambient air pollution is closely
associated with increased respiratory inflammation and decreased lung function. Particulate …

Pro‐inflammatory response and oxidative stress induced by specific components in ambient particulate matter in human bronchial epithelial cells

L Yang, G Liu, Z Lin, Y Wang, H He, T Liu… - Environmental …, 2016 - Wiley Online Library
Previous studies have shown that biological effect of particulate matter (PM2. 5) is involved
in including chemical composition and mass concentration, but the precise components and …

Exposure to PM2. 5 induces aberrant activation of NF-κB in human airway epithelial cells by downregulating miR-331 expression

L Song, D Li, X Li, L Ma, X Bai, Z Wen, X Zhang… - Environmental …, 2017 - Elsevier
Exposure to particulate matter (PM) with an aerodynamic diameter≤ 2.5 μm (PM2. 5)
induces reactive oxygen species (ROS) and pro-inflammatory cytokine production, leading …

Urban particulate matter (PM) suppresses airway antibacterial defence

X Chen, J Liu, J Zhou, J Wang, C Chen, Y Song… - Respiratory …, 2018 - Springer
Background Epidemiological studies have shown that urban particulate matter (PM)
increases the risk of respiratory infection. However, the underlying mechanisms are poorly …

Particulate matter disrupts human lung endothelial barrier integrity via ROS-and p38 MAPK–dependent pathways

T Wang, ET Chiang, L Moreno-Vinasco… - American journal of …, 2010 - atsjournals.org
Epidemiologic studies have linked exposure to airborne pollutant particulate matter (PM)
with increased cardiopulmonary mortality and morbidity. The mechanisms of PM-mediated …

Airborne particulate matter selectively activates endoplasmic reticulum stress response in the lung and liver tissues

S Laing, G Wang, T Briazova… - … of physiology-cell …, 2010 - journals.physiology.org
Recent studies have suggested a link between inhaled particulate matter (PM) exposure
and increased mortality and morbidity associated with pulmonary and cardiovascular …