Despite advances in cancer therapy, effective local treatment remains a formidable
challenge due to the limit of efficient drug delivery method and the toxicity of …

Since the anticancer drugs exhibited a variety of inhibitory mechanisms in cancer cells, the
use of two or more anticancer drugs may have excellent therapeutic effects, particularly in …

A pulmonary codelivery system that can simultaneously deliver doxorubicin (DOX) and Bcl2
siRNA to the lungs provides a promising local treatment strategy for lung cancers. In this …

Background and Oobjectives: Lung cancer, a pressing issue in present-day society due to its
high prevalence and mortality rate, can be managed effectively by long-term delivery of …

An amphiphilic copolymer, folic acid (FA) modified poly (ethylene glycol)-poly (lactic-co-
glycolic acid)(FA-PEG-PLGA) was prepared and explored as a nanometer carrier for the co …

Context: Paclitaxel (PTX) and carboplatin (CBP) are widely used for the combined
chemotherapy of non-small cell lung cancer (NSCLC). However, the development of …

Low targeting efficiency limits the applications of nanoparticles in cancer therapy. The fact
that mesenchymal stem cells (MSC) trapped in the lung after systemic infusion is a …

Lung cancer is the second most prevalent and the deadliest among all cancer types.
Chemotherapy is recommended for lung cancers to control tumor growth and to prolong …

Doxorubicin-loaded nanoparticles (NPs) were incorporated into inhalable effervescent and
non-effervescent carrier particles using a spray–freeze drying technique. The prepared …

Background Inhalation of chemotherapeutic drugs directly into the lungs augments the drug
exposure to lung cancers. The inhalation of free drugs however results in over exposure and …