Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease resulting in the destruction
of insulin producing β-cells of the pancreas, with consequent insulin deficiency and …

Hyperglycemia exerts toxic effects on the pancreatic β-cells. This study investigated the
hypothesis that the common antidiabetic drugs glibenclamide and metformin, in combination …

Hyperglycemia-induced oxidative stress is a common phenomenon in diabetes. Since
oxidative stress depletes adiponectin and insulin levels, we investigated whether an …

Diabetes mellitus is the most common serious metabolic disorder and it is considered to be
one of the five leading causes of death in the world. Hyperglycemia-mediated oxidative …

The present study was aimed to evaluate the antioxidant defense system of cinnamaldehyde
in normal, diabetic rats and its possible protection of pancreatic β-cells against its gradual …

Background Diabetes mellitus type 1 is an autoimmune disorder caused by lymphocytic
infiltration and beta cells destruction. Curcumin has been identified as a potent inducer of …

Type 1 diabetes is characterized by insulin deficiency due to the destruction of pancreatic β
cells, leading to hyperglycemia, which in turn induces vascular complications. In the current …

Although there is a therapeutic treatment to combat diabetes, the identification of agents that
may deal with its more serious aspects is an important medical field for research. Diabetes …

Abnormal regulation of glucose and impaired carbohydrate utilization that result from a
defective or deficient insulin are the key pathogenic events in type 2 diabetes mellitus …

Aims There is a close link between oxidative stress, inflammation, and type 2 diabetes
mellitus (T2DM). Gentisic acid (GA) is a di-phenolic compound and an active metabolite of …