Treatment with ferulic acid to rats with streptozotocin-induced diabetes: effects on oxidative stress, pro-inflammatory cytokines, and apoptosis in the pancreatic β cell

S Roy, SK Metya, S Sannigrahi, N Rahaman, F Ahmed - Endocrine, 2013 - Springer
In the present study, we aimed to investigate the protective effect of ferulic acid at different
doses (50 mg/kg alternative day and 50 mg/kg daily) on diabetic rats and to explore the …

Anti-diabetic study of vitamin B6 on hyperglycaemia induced protein carbonylation, DNA damage and ROS production in alloxan induced diabetic rats

KM Abdullah, F Abul Qais, H Hasan… - Toxicology …, 2019 - academic.oup.com
Oxidative stress performs an imperative role in the onset and progression of diabetes.
Metabolic enzymes and cellular organelles are detrimental to increased levels of free …

Allium hookeri root protects oxidative stress-induced inflammatory responses and β-cell damage in pancreas of streptozotocin-induced diabetic rats

SS Roh, OJ Kwon, JH Yang, YS Kim, SH Lee… - … and Alternative Medicine, 2016 - Springer
Background Water extract from the root of Allium hookeri (AH) shows anti-inflammatory,
antioxidant, and free radical scavenging effects. In this study, the ameliorating effects of AH …

Effect of CAPE-pNO2 against type 2 diabetes mellitus via the AMPK/GLUT4/GSK3β/PPARα pathway in HFD/STZ-induced diabetic mice

S Li, Q Huang, L Zhang, X Qiao, Y Zhang… - European journal of …, 2019 - Elsevier
Abstract CAPE-pNO 2, a para-nitro derivative of caffeic acid phenethyl ester (CAPE), has
been proved to exert stronger effects on diabetic complications in diabetic mice. The present …

Antihyperglycaemic, antilipid peroxidative and antioxidant effects of gallic acid on streptozotocin induced diabetic Wistar rats

VR Punithavathi, PSM Prince, R Kumar… - European journal of …, 2011 - Elsevier
The present study aims to evaluate the antihyperglycaemic, antilipid peroxidative and
antioxidant effects of gallic acid on streptozotocin induced diabetic male Wistar rats. To …

Neuromodulatory effects of hesperidin in mitigating oxidative stress in streptozotocin induced diabetes

M Ashafaq, L Varshney, MHA Khan… - BioMed research …, 2014 - Wiley Online Library
Oxidative stress has been implicated in pathogenesis of streptozotocin‐(STZ‐) induced
diabetes mellitus and its complication in central nervous system (CNS). Recent studies have …

Ameliorative effect of diosmin, a citrus flavonoid against streptozotocin-nicotinamide generated oxidative stress induced diabetic rats

S Srinivasan, L Pari - Chemico-Biological Interactions, 2012 - Elsevier
Oxidative stress has been suggested as a contributory factor in development and
complication of diabetes. The aim of the study was to evaluate the effect of diosmin (DS) in …

The association effect of insulin and clonazepam on oxidative stress in liver of an experimental animal model of diabetes and depression

CAY Wayhs, C Tortato, CP Mescka… - Pharmaceutical …, 2013 - Taylor & Francis
Context: It is known that oxidative stress occurs in peripheral blood in an experimental
animal model of diabetes and depression, and acute treatment with insulin and clonazepam …

Sulfonylurea as well as elevated glucose levels stimulate reactive oxygen species production in the pancreatic β-cell line, MIN6—a role of NAD (P) H oxidase in β …

H Tsubouchi, T Inoguchi, M Inuo, M Kakimoto… - Biochemical and …, 2004 - Elsevier
Increased oxidative stress may play a key role in the progressive deterioration of pancreatic
β-cells and the development of diabetes. However, the underlying mechanism is not well …

Antihyperglycemic and antioxidant properties of caffeic acid in db/db mice

UJ Jung, MK Lee, YB Park, SM Jeon, MS Choi - Journal of pharmacology …, 2006 - ASPET
This study investigated the blood glucose-lowering effect and antioxidant capacity of caffeic
acid in C57BL/KsJ-db/db mice. Caffeic acid induced a significant reduction of the blood …