Purpose: The aim of this study was to provide insight in the use, intensity and toxicity of
therapy with capecitabine and oxaliplatin (CAPOX) and capecitabine monotherapy …

The aim of this study is to investigate the effects of CAPOX and capecitabine on recurrence‐
free survival (RFS) and overall survival (OS) among elderly stage III colon cancer patients …

Background To determine the efficacy and tolerability of capecitabine combined with
oxaliplatin (CAPOX) or irinotecan (CAPIRI) as first-line treatment in patients with …

Introduction: Adjuvant chemotherapy improves the prognosis of patients with colorectal
cancer (CRC) following radical resection. However, the safety and efficacy of oxaliplatin …

Background Adjuvant capecitabine and oxaliplatin (CAPOX) is a standard treatment for
resected colon cancer; however, in patients with moderate renal impairment, the incidence …

Purpose 45% of colon cancer patients are elderly, yet they are often deviated from standard
cancer management. The MOSAIC trial favored FOLFOX over FL with superior oncologic …

Background Over half of the patients were diagnosed with colorectal cancer after 70 years of
age. The choice of the most suitable chemotherapy strategy is the major challenge for …

Abstract Introduction/Background Adjuvant treatment of colon cancer relies on
fluoropyrimidine-containing regimens as the intravenous formulation, 5-FU, or its oral …

Background This study was conducted to analyze the feasibility of adjuvant capecitabine
therapy using a tailored-dose escalation strategy in elderly patients with colon cancer (CC) …

This study aimed to compare efficacy and toxicity of palliative chemotherapy for elderly and
younger colorectal cancer patients. Patients aged 24–69 (n= 203) and 70–82 years (n= 57) …