The Population Structure of Pseudomonas aeruginosa Is Characterized by Genetic Isolation of exoU+ and exoS+ Lineages

EA Ozer, E Nnah, X Didelot, RJ Whitaker… - Genome biology and …, 2019 - academic.oup.com
The diversification of microbial populations may be driven by many factors including
adaptation to distinct ecological niches and barriers to recombination. We examined the …

Environmental reservoirs for exoS+ and exoU+ strains of Pseudomonas aeruginosa

V Rutherford, K Yom, EA Ozer, O Pura… - Environmental …, 2018 - Wiley Online Library
Pseudomonas aeruginosa uses its type III secretion system to inject the effector proteins
ExoS and ExoU into eukaryotic cells, which subverts these cells to the bacterium's …

Phenotypic and genomic comparison of the two most common ExoU-positive Pseudomonas aeruginosa clones, PA14 and ST235

S Fischer, S Dethlefsen, J Klockgether, B Tümmler - Msystems, 2020 - Am Soc Microbiol
Genotyping of 2,882 Pseudomonas aeruginosa isolates that had been collected during the
last 40 years identified the ExoU-positive lineages PA14 (ST253) and ST235 as the second …

Prevalence of type III secretion genes in clinical and environmental isolates of Pseudomonas aeruginosa

H Feltman, G Schulert, S Khan, M Jain… - …, 2001 - microbiologyresearch.org
The type III secretion system of Pseudomonas aeruginosa transports four known effector
proteins: ExoS, ExoT, ExoU and ExoY. However, the prevalence of the type III secretion …

Genome-Wide Patterns of Recombination in the Opportunistic Human Pathogen Pseudomonas aeruginosa

JR Dettman, N Rodrigue… - Genome biology and …, 2015 - academic.oup.com
The bacterium Pseudomonas aeruginosa is a significant cause of acute nosocomial
infections as well as chronic respiratory infections in patients with cystic fibrosis (CF). Recent …

Conservation of genome content and virulence determinants among clinical and environmental isolates of Pseudomonas aeruginosa

MC Wolfgang, BR Kulasekara… - Proceedings of the …, 2003 - National Acad Sciences
Pseudomonas aeruginosa is a ubiquitous environmental bacterium capable of causing a
variety of life-threatening human infections. The genetic basis for preferential infection of …

Pseudomonas genomes: diverse and adaptable

MW Silby, C Winstanley, SAC Godfrey… - FEMS microbiology …, 2011 - academic.oup.com
Members of the genus Pseudomonas inhabit a wide variety of environments, which is
reflected in their versatile metabolic capacity and broad potential for adaptation to fluctuating …

High frequency of the exoU+/exoS+ genotype associated with multidrug-resistant “high-risk clones” of Pseudomonas aeruginosa clinical isolates from Peruvian …

G Horna, C Amaro, A Palacios, H Guerra, J Ruiz - Scientific Reports, 2019 - nature.com
The type III secretion system of Pseudomonas aeruginosa is an important virulence factor
contributing to the cytotoxicity and the invasion process of this microorganism. The current …

Draft genomes of 12 host-adapted and environmental isolates of Pseudomonas aeruginosa and their positions in the core genome phylogeny

L Stewart, A Ford, V Sangal, J Jeukens… - Pathogens and …, 2014 - academic.oup.com
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen particularly
associated with the inherited disease cystic fibrosis (CF). Pseudomonas aeruginosa is well …

Pseudomonas aeruginosa renews its virulence factors

P Huber, P Basso, E Reboud… - Environmental …, 2016 - Wiley Online Library
Highly divergent strains of the major human opportunistic pathogen Pseudomonas
aeruginosa have been isolated around the world by different research laboratories. They …