Background Joint replacement implants are usually manufactured from cobalt-chromium or
titanium alloys. After the device is implanted, wear and corrosion generate metal particles …

Background Hip implants are usually manufactured from cobalt-chromium and titanium
alloys. As the implants wear and corrode, metal debris is released into the surrounding …

In April 2010, a Medicines and Healthcare Products Regulatory Agency safety alert
concerning all metal-on-metal (MOM) hip replacements recommended measuring chromium …

Individuals with advanced hip disease suffer from pain, impaired hip function, and
decreased quality of life. Roughly one million metal-on-metal (MoM) hip prostheses have …

Background Orthopaedic implants made of cobalt-chromium alloy undergo wear and
corrosion that can lead to deposition of cobalt and chromium in vital organs. Elevated …

Introduction Stainless steel and commercially pure titanium are widely used materials in
orthopedic implants. However, it is still being controversially discussed whether there are …

Although devices made of titanium and its alloy with 6% aluminium and 4% vanadium have
been remarkably successful primarily in orthopaedic and dental applications, clinical reports …

Increased concentrations of circulating metal-degradation products derived from the use of
Ti orthopaedic implants may have deleterious biological effects over the long term …

Metallic implants placed in humans exhibit wear and corrosion that result in the liberation of
metal-containing by-products. In the case of titanium (Ti) containing implants, the metal …

Metal ions generated from joint replacements are a cause for concern. There is no
consensus on the best surrogate measure of metal ion exposure. This study investigates …