Assessment of tobacco specific nitrosamines (TSNAs) in oral fluid as biomarkers of cancer risk: A population-based study

R Pérez-Ortuño, JM Martínez-Sánchez, M Fu… - Environmental …, 2016 - Elsevier
Background Smoke-free laws are expected to reduce smoking habits and exposure to
secondhand smoke. The objective of this study was the measurement of tobacco specific …

Determination of tobacco-specific N-nitrosamines in urine of smokers and non-smokers

D Kavvadias, G Scherer, F Cheung, G Errington… - Biomarkers, 2009 - Taylor & Francis
Tobacco-specific N-nitrosamines (TSNA) include 4-(methylnitrosamino)-1-(3-pyridyl)-1-
butanone (NNK), N′-nitroso nornicotine (NNN), N′-nitroso anabasine (NAB) and N …

Effect of differing levels of tobacco-specific nitrosamines in cigarette smoke on the levels of biomarkers in smokers

DL Ashley, RJ O'Connor, JT Bernert, CH Watson… - … , biomarkers & prevention, 2010 - AACR
Background: Smokers are exposed to significant doses of carcinogens, including tobacco-
specific nitrosamines (TSNA). Previous studies have shown significant global differences in …

Investigation of exposure biomarkers in human plasma following differing levels of tobacco-specific N-nitrosamines and nicotine in cigarette smoke

J Zhang, X Liu, B Shi, Z Yang, Y Luo, T Xu, D Liu… - Environmental …, 2022 - Elsevier
Tobacco-specific N-nitrosamines (TSNAs) are strong carcinogens widely found in tobacco
products, environmental tobacco smoke, lake, and wastewater. The main objective of this …

Tobacco-specific nitrosamines (NNAL, NNN, NAT, and NAB) exposures in the US Population Assessment of Tobacco and Health (PATH) Study Wave 1 (2013–2014)

B Xia, BC Blount, T Guillot, C Brosius… - Nicotine and …, 2021 - academic.oup.com
Introduction The tobacco-specific nitrosamines (TSNAs) are an important group of
carcinogens found in tobacco and tobacco smoke. To describe and characterize the levels …

Simultaneous determination of four tobacco-specific N-nitrosamines (TSNA) in human urine

D Kavvadias, G Scherer, M Urban, F Cheung… - … of Chromatography B, 2009 - Elsevier
Tobacco-specific N-nitrosamines (TSNA) include 4-(methylnitrosamino)-1-(3-pyridyl)-1-
butanone (NNK), N-nitrosonornicotine (NNN), N-nitrosoanabasine (NAB) and N …

TSNA exposure: levels of NNAL among Canadian tobacco users

CD Czoli, D Hammond - Nicotine & Tobacco Research, 2015 - academic.oup.com
Introduction: Tobacco smoke contains more than 7,000 chemicals, including known
carcinogens, such as tobacco-specific nitrosamines (TSNAs). TSNA levels in cigarettes vary …

Tobacco-specific nitrosamine exposures in smokers and nonsmokers exposed to cigarette or waterpipe tobacco smoke

G Radwan, SS Hecht, SG Carmella… - Nicotine & Tobacco …, 2012 - academic.oup.com
Introduction: The causal relationship between tobacco smoking and a variety of cancers is
attributable to the carcinogens that smokers inhale, including tobacco-specific nitrosamines …

Detection and Quantitation of N′-Nitrosonornicotine in Human Toenails by Liquid Chromatography-Electrospray Ionization-Tandem Mass Spectrometry

I Stepanov, SS Hecht - Cancer Epidemiology Biomarkers & Prevention, 2008 - AACR
Specific biomarkers of tobacco carcinogen uptake are critical for investigations of the role of
tobacco smoke exposure in human cancers. Two new biomarkers of human exposure to …

Simultaneous determination of five tobacco-specific nitrosamines in mainstream cigarette smoke by isotope dilution liquid chromatography/electrospray ionization …

W Wu, DL Ashley, CH Watson - Analytical Chemistry, 2003 - ACS Publications
Tobacco-specific nitrosamines (TSNAs) have been previously implicated as a source of
carcinogenicity in tobacco and cigarette smoke. Accurate quantification of these chemicals is …