Regional versus General Anesthesia for Promoting Independence after Hip Fracture (REGAIN): protocol for a pragmatic, international multicentre trial

MD Neuman, SS Ellenberg, FE Sieber, JS Magaziner… - BMJ open, 2016 - bmjopen.bmj.com
Introduction Hip fractures occur 1.6 million times each year worldwide, with substantial
associated mortality and losses of independence. At present, anaesthesia care for hip …

Long-term Outcomes with Spinal versus General Anesthesia for Hip Fracture Surgery: A Randomized Trial

EA Vail, R Feng, F Sieber, JL Carson, SS Ellenberg… - …, 2024 - pubs.asahq.org
Background The effects of spinal versus general anesthesia on long-term outcomes have
not been well studied. This study tested the hypothesis that spinal anesthesia is associated …

Improve hip fracture outcome in the elderly patient (iHOPE): a study protocol for a pragmatic, multicentre randomised controlled trial to test the efficacy of spinal versus …

A Kowark, C Adam, J Ahrens, M Bajbouj… - BMJ open, 2018 - bmjopen.bmj.com
Introduction Hip fracture surgery is associated with high in-hospital and 30-day mortality
rates and serious adverse patient outcomes. Evidence from randomised controlled trials …

Pain, analgesic use, and patient satisfaction with spinal versus general anesthesia for hip fracture surgery: a randomized clinical trial

MD Neuman, R Feng, SS Ellenberg… - Annals of internal …, 2022 - acpjournals.org
Background: The REGAIN (Regional versus General Anesthesia for Promoting
Independence after Hip Fracture) trial found similar ambulation and survival at 60 days with …

The influence of mode of anaesthesia on perioperative outcomes in people with hip fracture: a prospective cohort study from the National Hip Fracture Database for …

GS Matharu, A Shah, S Hawley, A Johansen, D Inman… - BMC medicine, 2022 - Springer
Background Delirium is common after hip fracture surgery, affecting up to 50% of patients.
The incidence of delirium may be influenced by mode and conduct of anaesthesia. We …

[HTML][HTML] Clinical effectiveness and safety of spinal anaesthesia compared with general anaesthesia in patients undergoing hip fracture surgery using a consensus …

SK Kunutsor, PB Hamal, S Tomassini, J Yeung… - British Journal of …, 2022 - Elsevier
Background We conducted a systematic review and meta-analysis of contemporary RCTs to
determine the clinical effectiveness of spinal vs general anaesthesia (SA vs GA) in patients …

[HTML][HTML] Perioperative outcomes in the context of mode of anaesthesia for patients undergoing hip fracture surgery: systematic review and meta-analysis

CM O'donnell, L McLoughlin, CC Patterson… - British journal of …, 2018 - Elsevier
Background Previous meta-analyses on the anaesthetic management of patients
undergoing surgery for hip fracture have focused on randomized trials. Furthermore …

Spinal or general anaesthesia for surgical repair of hip fracture and subsequent risk of mortality and morbidity: a database analysis using propensity score‐matching

L Morgan, TM McKeever, J Nightingale… - …, 2020 - Wiley Online Library
Around 76,000 people fracture their hip annually in the UK at a considerable personal,
social and financial cost. Despite longstanding debate, the optimal mode of anaesthesia …

General vs. neuraxial anaesthesia in hip fracture patients: a systematic review and meta-analysis

J Van Waesberghe, A Stevanovic, R Rossaint… - BMC …, 2017 - Springer
Background Hip fracture is a trauma of the elderly. The worldwide number of patients in
need of surgery after hip fracture will increase in the coming years. The 30-day mortality …

Comparison of general anaesthesia and regional anaesthesia in terms of mortality and complications in elderly patients with hip fracture: a nationwide population …

EJ Ahn, HJ Kim, KW Kim, HR Choi, H Kang… - BMJ open, 2019 - bmjopen.bmj.com
Objective To evaluate the effects of anaesthesia on postoperative outcome in elderly
patients who underwent hip fracture surgery. Setting Nationwide National Health Insurance …