Studies on the mechanism of the enhancement of the antihypertensive activity of captopril by a diuretic in spontaneously hypertensive rats

FM Lai, T Tanikella, H Herzlinger… - … Hypertension. Part A …, 1982 - Taylor & Francis
Captopril (30 mg/kg/day orally for two days) in spontaneously hypertensive rats (SHR)
inhibited serum angiotensin converting enzyme (ACE) activity 92.3%; increased plasma …

Red blood cell rheological properties in various rat hypertension models

G Hacioglu, O Yalcin, M Bor‐Kucukatay… - Clinical …, 2002 - content.iospress.com
Red blood cell (RBC) properties were proposed to play role in the development of
hypertension (HT). This study aimed at investigating the alterations of RBC deformability and …

The effect of a converting enzyme inhibitor upon renal damage in spontaneously hypertensive Fawn Hooded rats

PJ Westenend, YA Nooyen, JA van der Krogt… - Journal of …, 1992 - journals.lww.com
Objective: To determine the effect of angiotensin converting enzyme inhibition (CEI) upon
renal function and the incidence of glomerulosclerosis in spontaneously hypertensive Fawn …

Flow resistance and its components in hypertensive men treated with the calcium antagonist isradipine

M Wysocki, B Persson, U Bagge… - European journal of …, 1992 - Springer
The components of blood flow resistance were investigated in 14 men with essential
hypertension (diastolic blood pressure higher or equal to 100 mmHg) before and after …

Chronic treatment with captopril, SQ 29,852, hydralazine and a 33% fish meal diet in malignant stroke-prone spontaneously hypertensive rats

K Okamoto, Y Ohta, T Chikugo, H Shiokawa… - Journal of …, 1991 - journals.lww.com
Malignant stroke-prone spontaneously hypertensive rats (M-SHRSP) are a useful animal
model for studying juvenile malignant hypertension. Using M-SHRSP males, the effects of …

Captopril reduces aortic and microvascular growth in hypertensive and normotensive rats.

DH Wang, RL Prewitt - Hypertension, 1990 - Am Heart Assoc
This experiment was designed to investigate the effect of converting enzyme inhibition on
functional and structural vascular alterations in one-kidney, one clip hypertensive rats and in …

Captopril, blood pressure, and vascular reactivity in psychosocial hypertensive mice

CR Webb, MN Hamlin, JP Henry… - …, 1986 - augusta.elsevierpure.com
Sustained hypertension can be induced in CBA mice by exposure to social stress in a
complex population cage. At 1 week the hypertension is not altered by short-term …

Ramipril therapy improves arterial dilation in experimental hypertension

N Hutri-Kähönen, M Kähönen… - Cardiovascular …, 1997 - academic.oup.com
Objective: Angiotensin-converting enzyme (ACE) inhibition has been shown to restore
impaired endothelial function in hypertension, but the roles of different mediators in …

S‐Allyl‐Mercapto‐Captopril: A novel compound in the treatment of cohen‐rosenthal diabetic hypertensive rats

F Younis, D Mirelman, A Rabinkov… - The Journal of Clinical …, 2010 - Wiley Online Library
J Clin Hypertens (Greenwich). 2010; 12: 451–455.© 2010 Wiley Periodicals, Inc. S‐allyl‐
mercapto‐captopril (CPSSA) is a conjugate of captopril with allicin, an active principle in …

Prevention of the development of spontaneous hypertension in rats by captopril (SQ 14,225)

RA Ferrone, MJ Antonaccio - European journal of pharmacology, 1979 - Elsevier
Indirect systolic blood pressure (SBP) was monitored in male, spontaneously hypertensive
rats (SHR) maintained on water for 16 weeks (group A) or on captopril therapy (100 …