Background Papillary thyroid carcinoma (PTC) is a common endocrine neoplasm with a
recent increase in incidence in many countries. Although PTC has been explored by gene …

Context: Aberrant DNA methylation is known to be a major factor in oncogenesis and cancer
progression, but effects of methylation in papillary thyroid cancer (PTC) are not well defined …

Thyroid cancer is a heterogeneous disease with several subtypes characterized by
cytological, histological and genetic alterations, but the involvement of epigenetics is not …

Background Alterations in DNA methylation have been demonstrated in a variety of
malignancies, including papillary thyroid cancer (PTC). The full extent of dysregulation in …

Context Even though the majority of well-differentiated thyroid carcinoma (WDTC) is
indolent, a number of cases display an aggressive behavior. Cumulative evidence suggests …

The BRAF V600E mutation plays an important role in the tumorigenesis of papillary thyroid
cancer (PTC). To explore an epigenetic mechanism involved in this process, we performed a …

Background: There are no reliable biomarkers to accurately differentiate indolent thyroid
tumors from more aggressive thyroid cancers. This study aimed to develop new DNA …

Cancer arises through accumulation of epigenetic and genetic alteration. Aberrant promoter
methylation is a common epigenetic mechanism of gene silencing in cancer cells. We here …

Background: Alterations in DNA methylation are stable epigenetic events that can serve as
clinical biomarkers. The aim of this study was to analyze methylation patterns among various …

Simple Summary Epigenetic alterations are critical for tumor onset and development. DNA
methylation is one of the most studied pathways concerning various types of cancer. A …