The genetic information encoded in nuclear mRNA destined to reach the cytoplasm requires
the interaction of the mRNA molecule with the nuclear pore complex (NPC) for the process …

The nuclear pore complex is the gateway for protein and RNA transport between the
cytoplasm and nucleus. Recent work has characterized signals and components involved in …

Export of mRNA through nuclear pore complexes (NPC) is preceded by multiple and well
coordinated processing steps, resulting in the formation of an export competent …

The nuclear pore complex (NPC) serves as a central gate for mRNAs to transit from the
nucleus to the cytoplasm. The ability for mRNAs to get exported is linked to various upstream …

Nuclear mRNA export through the nuclear pore complex has been proposed to be a
unidirectional, signal-mediated and energy-dependent process. Evidence exists that this …

Over the last two decades, multiple studies have explored the mechanisms governing
mRNA export out of the nucleus, a crucial step in eukaryotic gene expression. During …

Transcribed mRNA molecules must reach the cytoplasm to undergo translation.
Technological developments in imaging have placed mRNAs under the spotlight, allowing …

Cellular mRNAs are produced in the nucleus and must be exported to the cytoplasm to allow
for their translation into proteins. Recruitment of export factors to nascent mRNA starts …

The changes occurring in mRNA organization during nucleo-cytoplasmic transport and
export, are not well understood. Moreover, directionality of mRNA passage through the …

Regulation of gene expression can occur at many different levels. One important step in the
gene expression process is the transport of mRNA from the nucleus to the cytoplasm. In …