Since the 1989 pro-democracy movement, which the Chinese Communist Party (CCP)
crushed so violently at Tiananmen Square, most organized Chinese political movements …

Introduction The function of a tissue and, therefore, the health of an organism can be
compromised by the presence of mutant or unfit cells. Cell competition is a mechanism that …

The Drosophila larval cellular immune response involves cells (hemocytes) that can be
recruited from a hematopoietic organ located behind the brain, as well as a sessile …

It has been reported that during Drosophila embryonic development, and in cell culture, that
the Rac GTPases are redundant. To better elucidate Rac function in Drosophila, we decided …

This thesis contains two chapters. In Chapter 1, we focused on the mechanisms underlying
host defense in response to specialist wasps of D. melanogaster, Leptopilina boulardi …

Recent studies suggest that mammalian hematopoietic stem and progenitor cells (HSPCs)
respond directly to infection and inflammatory signaling. These signaling pathways also …

In the developing Drosophila embryo, specification of the dorsal-ventral axis depends on
signaling through the receptor Toll. Activation of Toll by its ligand Spaetzle leads to …

In general the work behind this thesis has revolved around the interesting pattern
recognition gene family PGRPs (peptidoglycan recognition proteins). In particular the …

Toll signaling pathway plays an important role in innate immunity of Drosophila
melanogaster and mammals. The activation and termination of Toll signaling are finely …

In many cell types it is evident that the small GTPases Rac and Rho regulate each other's
activities. What is unclear is exactly how this regulation occurs. To further elucidate this …