Cerebrovascular diseases, such as ischemic stroke, pose serious medical challenges
worldwide due to their high morbidity and mortality and limitations in clinical treatment …

Ferroptosis is a unique regulated cell death defined by the intracellular iron overload and
distinct biological features compared with other well-known programmed cell death …

Stroke is a serious threat to human survival and health due to its high morbidity and
mortality. The pathological mechanism of stroke is complex and involves various regulated …

Ischemic stroke is one of the main causes of high morbidity, mortality, and disability
worldwide; however, the treatment methods are limited and do not always achieve …

Emerging evidence suggests that ferroptosis, a unique regulated cell death modality that is
morphologically and mechanistically different from other forms of cell death, plays a vital role …

As a neurological disease with high morbidity, disability, and mortality, the pathological
mechanism underlying stroke involves complex processes such as neuroinflammation …

Ischemic stroke is an acute cerebrovascular disease with a high morbidity, mortality, and
disability rate. Persistent ischemia of brain tissue can cause irreversible damage to neurons …

Background Ferroptosis, as a new form of cell death, is different from other cell deaths such
as autophagy or senescence. Ferroptosis involves in the pathophysiological progress of …

Stroke is a common disease in clinical practice, which seriously endangers people's
physical and mental health. The neurovascular unit (NVU) plays a key role in the occurrence …

Oxidative stress is a key cause of ischemic stroke and an initiator of neuronal dysfunction
and death, mainly through the overproduction of peroxides and the depletion of antioxidants …