FOXP2 IS A NEW COMPONENT OF THE AUTISTIC SPECTRUM DISORDER PUZZLE.

ZA Al Ali, AA Yasseen… - Biochemical & Cellular …, 2022 - search.ebscohost.com
Eventhough genetic variables play a significant part in the genesis of autistic disorder (AD),
no specific genes have been linked to the condition. The 7q31 locus has been linked to ASD …

[PDF][PDF] FOXP2 is not a major susceptibility gene for autism or specific language impairment

DF Newbury, E Bonora, JA Lamb, SE Fisher… - The American Journal of …, 2002 - cell.com
The FOXP2 gene, located on human 7q31 (at the SPCH1 locus), encodes a transcription
factor containing a polyglutamine tract and a forkhead domain. FOXP2 is mutated in a …

Mutation screening of FOXP2 in individuals diagnosed with autistic disorder

J Gauthier, R Joober, L Mottron… - American Journal of …, 2003 - Wiley Online Library
Although it is well established that genetic factors play an important role in the etiology of
autistic disorder (AD), no specific genes have as yet been implicated. Genetic …

Association between the FOXP2 gene and autistic disorder in Chinese population

X Gong, M Jia, Y Ruan, M Shuang, J Liu… - American Journal of …, 2004 - Wiley Online Library
Several genomewide screens indicated that chromosome 7q was linked to autistic disorder.
FOXP2, located on 7q31, is a putative transcription factor containing a polyglutamine tract …

FOXP2: novel exons, splice variants, and CAG repeat length stability

HA Bruce, RL Margolis - Human genetics, 2002 - Springer
FOXP2 is a transcription factor containing a polyglutamine tract, a zinc-finger motif, and a
forkhead DNA-binding domain. The FOXP2 gene is located on 7q31. A missense mutation …

Molecular genetics of speech and language disorders

DF Newbury, AP Monaco - Current opinion in pediatrics, 2002 - journals.lww.com
In 2001, scientists characterized the first gene to be implicated in the cause of a speech and
language disorder (FOXP2). Although FOXP2 was discovered using a unique family in …

[PDF][PDF] De novo mutations in FOXP1 in cases with intellectual disability, autism, and language impairment

FF Hamdan, H Daoud, D Rochefort, A Piton… - The American Journal of …, 2010 - cell.com
Heterozygous mutations in FOXP2, which encodes a forkhead transcription factor, have
been shown to cause developmental verbal dyspraxia and language impairment. FOXP2 …

Absence of causative mutations and presence of autism-related allele in FOXP2 in Japanese autistic patients

H Li, T Yamagata, M Mori, MY Momoi - Brain and development, 2005 - Elsevier
We analyzed the FOXP2 gene, which encodes a putative transcription factor containing a
polyglutamine tract and a forkhead DNA-binding domain, for a possible causative mutation …

FOXP Genes, Neural Development, Speech and Language Disorders

H Takahashi, K Takahashi, FC Liu - … factors: vital elements in biology and …, 2010 - Springer
Foxp subfamily genes were recently recognized to be members of the Fox gene family. Foxp
subfamily members contain a zinc finger domain and a leucine zipper motif in addition to a …

[HTML][HTML] Increased gene expression of FOXP1 in patients with autism spectrum disorders

WH Chien, SSF Gau, CH Chen, WC Tsai, YY Wu… - Molecular autism, 2013 - Springer
Background Comparative gene expression profiling analysis is useful in discovering
differentially expressed genes associated with various diseases, including mental disorders …