Background Heterozygous disruption of FOXP2 causes a rare form of speech and language
impairment. Screens of the FOXP2 sequence in individuals with speech/language-related …

Genetic and clinical studies of speech and language disorders are providing starting points
to unravel underlying neurobiological mechanisms. The gene encoding the transcription …

The KE family represent the only documented case of single-gene inheritance of a speech
and language disorder. There has been some debate over the specificity of their impairment …

We report on a young male with moderate mental retardation, dysmorphic features, and
language delay who is deleted for 7q31. 1‐7q31. 31. His full karyotype is 46, XY, der (7) del …

Mutations in FOXP2, a member of the forkhead family of transcription factor genes, are the
only known cause of developmental speech and language disorders in humans. To date …

Human Genetics: The Evolving Story of FOXP2 Page 1 7. Graybiel, AM, and Ragsdale, CW,
Jr. (1978). Histochemically distinct compartments in the striatum of human, monkeys, and …

Haploinsufficiency of Forkhead box protein P1 (FOXP1), a highly conserved transcription
factor, leads to developmental delay, intellectual disability, autism spectrum disorder …

Abstract Autism Spectrum Disorders (ASD) are a group of heterogeneous
neurodevelopmental disorders associated with immune system dysregulation. There are …

FOXP1 (forkhead box protein P1) is a transcription factor involved in the development of
several tissues, including the brain. An emerging phenotype of patients with protein …

Developmental disorders affecting speech and language are highly heritable, but very little
is currently understood about the neuromolecular mechanisms that underlie these traits …