Regulatory T cell therapy for autoimmune disease
TY Ha - Immune Network, 2008 - synapse.koreamed.org
It has now been well documented in a variety of models that T regulatory T cells (Treg cells)
play a pivotal role in the maintenance of self-tolerance, T cell homeostasis, tumor, allergy …
play a pivotal role in the maintenance of self-tolerance, T cell homeostasis, tumor, allergy …
[HTML][HTML] Regulatory T cell-based therapies for autoimmunity
B Arellano, DJ Graber, CL Sentman - Discovery medicine, 2016 - ncbi.nlm.nih.gov
Autoimmune disorders are long-term diseases that adversely affect the quality of life for
patients, and they are one of the top ten leading causes of death. While each autoimmune …
patients, and they are one of the top ten leading causes of death. While each autoimmune …
Treg cell-based therapies: challenges and perspectives
C Raffin, LT Vo, JA Bluestone - Nature Reviews Immunology, 2020 - nature.com
Cellular therapies using regulatory T (Treg) cells are currently undergoing clinical trials for
the treatment of autoimmune diseases, transplant rejection and graft-versus-host disease. In …
the treatment of autoimmune diseases, transplant rejection and graft-versus-host disease. In …
The therapeutic potential of regulatory T cells for the treatment of autoimmune disease
JA Bluestone, E Trotta, D Xu - Expert opinion on therapeutic targets, 2015 - Taylor & Francis
Introduction: Immune tolerance remains the holy grail of therapeutic immunology in the fields
of organ and tissue transplant rejection, autoimmune diseases, and allergy and asthma. We …
of organ and tissue transplant rejection, autoimmune diseases, and allergy and asthma. We …
[HTML][HTML] Regulatory T cells as immunotherapy
BD Singer, LS King, FR D'Alessio - Frontiers in immunology, 2014 - frontiersin.org
Regulatory T cells (Tregs) suppress exuberant immune system activation and promote
immunologic tolerance. Because Tregs modulate both innate and adaptive immunity, the …
immunologic tolerance. Because Tregs modulate both innate and adaptive immunity, the …
Regulatory T cells for immunotherapy of autoimmune diseases: from the bench to the bedside
The induction of antigen-specific unresponsiveness or tolerance is critical for the prevention
of autoimmunity and maintenance of immune homeostasis. The presence of regulatory T …
of autoimmunity and maintenance of immune homeostasis. The presence of regulatory T …
Regulatory T cells
Recent advances in the study of regulatory T cells (Tregs) highlight their essential role in
maintaining the immune system's homeostasis and treating autoimmune diseases …
maintaining the immune system's homeostasis and treating autoimmune diseases …
Regulatory T cells: a review.
A Dasgupta, R Saxena - The National medical journal of India, 2012 - europepmc.org
Regulatory T cells (Tregs) play a pivotal role in the homeostasis of the immune system and
in the modulation of the immune response. Tregs have emerged as key players in the …
in the modulation of the immune response. Tregs have emerged as key players in the …
Next-generation regulatory T cell therapy
Regulatory T cells (Treg cells) are a small subset of immune cells that are dedicated to
curbing excessive immune activation and maintaining immune homeostasis. Accordingly …
curbing excessive immune activation and maintaining immune homeostasis. Accordingly …
[PDF][PDF] Therapeutic potential of T regulatory cell manipulation: advantages and limitations
A Neagu, C Mambet, LG Necula, L Matei… - Rom Biotechnol …, 2018 - e-repository.org
Regulatory T cells have a central role in maintaining immune homeostasis by modulating
immune responses and promoting tolerance to self-antigens. Treg cells are involved in …
immune responses and promoting tolerance to self-antigens. Treg cells are involved in …