After renal transplantation, recurrence of the original disease is the second most common
cause of graft loss, after rejection. The most dramatic manifestation of this phenomenon is in …

Background Genetic defects in podocyte proteins account for up to 30% of steroid-resistant
nephrotic syndrome (SRNS) in the paediatric population. Most children with genetic SRNS …

Idiopathic nephrotic syndrome is the most common glomerular disorder of childhood.
Recurrence of nephrotic syndrome immediately following renal transplantation is rapid …

Identification of genes associated with childhood-onset nephrotic syndrome has significantly
advanced our understanding of the pathogenesis of this complex disease over the past two …

Nephrotic syndrome (NS) is a clinical entity characterized by proteinuria, hypoalbuminemia,
and peripheral edema. NS affects about 2–7 per 100,000 children aged below 18 years old …

Nephrotic syndrome (NS) is one of the most challenging conditions to manage and treat,
partly because we lack a specific molecular understanding of its pathogenesis and …

Two histological subtypes of idiopathic nephrotic syndrome are commonly recognized in
children, namely minimal change nephropathy and focal segmental glomerulosclerosis …

Nephrotic syndrome (NS) is a clinical condition characterized by proteinuria, a reduction in
serum levels of albumin and other proteins, edema, hypercholesterolemia, and often …

Nephrotic syndrome (NS) is a common pediatric kidney disease and is defined as massive
proteinuria, hypoalbuminemia, and edema. Dysfunction of the glomerular filtration barrier …

Exciting recent findings in the genotypic/phenotypic correlations of patients with congenital
nephrotic syndrome may not only modify our understanding of this disease but may also …