Reclassifying acute respiratory distress syndrome

G Maiolo, F Collino, F Vasques, F Rapetti… - American journal of …, 2018 - atsjournals.org
Rationale: The ratio of PaO2 to FiO2 (P/F) defines acute respiratory distress syndrome
(ARDS) severity and suggests appropriate therapies. Objectives: We investigated 1) whether …

The value of positive end-expiratory pressure and Fio2 criteria in the definition of the acute respiratory distress syndrome

M Britos, E Smoot, KD Liu, BT Thompson… - Critical care …, 2011 - journals.lww.com
Objectives: The criteria that define acute lung injury and the acute respiratory distress
syndrome include PaO 2/Fio 2 but not positive end-expiratory pressure or Fio 2. PaO 2/Fio 2 …

[HTML][HTML] A universal definition of ARDS: the PaO2/FiO2 ratio under a standard ventilatory setting—a prospective, multicenter validation study

J Villar, L Pérez-Méndez, J Blanco, JM Añón… - Intensive care …, 2013 - Springer
Abstract Purpose The PaO 2/FiO 2 is an integral part of the assessment of patients with
acute respiratory distress syndrome (ARDS). The American-European Consensus …

A clinical classification of the acute respiratory distress syndrome for predicting outcome and guiding medical therapy

J Villar, RL Fernández, A Ambrós, L Parra… - Critical care …, 2015 - journals.lww.com
Objective: Current in-hospital mortality of the acute respiratory distress syndrome (ARDS) is
above 40%. ARDS outcome depends on the lung injury severity within the first 24 hours of …

An Early PEEP/FiO2 Trial Identifies Different Degrees of Lung Injury in Patients with Acute Respiratory Distress Syndrome

J Villar, L Pérez-Méndez, J López, J Belda… - American journal of …, 2007 - atsjournals.org
Rationale: Current American-European Consensus Conference definitions for acute lung
injury (ALI) and acute respiratory distress syndrome (ARDS) are inadequate for inclusion …

Current definitions of acute lung injury and the acute respiratory distress syndrome do not reflect their true severity and outcome

J Villar, L Perez-Mendez, RM Kacmarek - Intensive care medicine, 1999 - Springer
Background: Despite intensive research, there are no universally accepted clinical
definitions for acute lung injury (ALI) or the acute respiratory distress syndrome (ARDS). A …

The acute respiratory distress syndrome: Definitions, severity and clinical outcome An analysis of 101 clinical investigations

P Krafft, P Fridrich, T Pernerstorfer, RD Fitzgerald… - Intensive care …, 1996 - Springer
Objective To determine possible changes in outcome from acute respiratory distress
syndrome (ARDS) and to compare severity of lung injury and methods of treatment from …

[HTML][HTML] Redefining ARDS: a paradigm shift

J Villar, T Szakmany, G Grasselli, L Camporota - Critical Care, 2023 - Springer
Although the defining elements of “acute respiratory distress syndrome”(ARDS) have been
known for over a century, the syndrome was first described in 1967. Since then, despite …

[HTML][HTML] Pathophysiology and biomarkers of acute respiratory distress syndrome

S Fujishima - Journal of intensive care, 2014 - Springer
Acute respiratory distress syndrome (ARDS) is defined as an acute-onset, progressive,
hypoxic condition with radiographic bilateral lung infiltration, which develops after several …

[HTML][HTML] Relation between PaO2/FIO2 ratio and FIO2: a mathematical description

J Aboab, B Louis, B Jonson, L Brochard - Intensive care medicine, 2006 - Springer
The acute respiratory distress syndrome (ARDS) is characterized by severe hypoxemia, a
cornerstone element in its definition. Numerous indices have been used to describe this …