Suramin was the first urea-based drug to be approved in the clinic, and in the following
century, a number of milestone drugs based on this scaffold were developed. Indeed, urea …

The diaryl urea is an important fragment/pharmacophore in constructing anticancer
molecules due to its near-perfect binding with certain acceptors. The urea NH moiety is a …

Within the past ten years, a huge volume of research on the synthesis, structure-activity
relationships (SAR), and anticancer activities of the urea derivatives was reported. Many …

The urea functionality is inherent to numerous bioactive compounds, including a variety of
clinically approved therapies. Urea containing compounds are increasingly used in …

The malignant neoplasm, which is recognized as cancer, is a serious threat to human health
and frequently-occurring disease. Diphenylurea, an important link structure in the design of …

Twenty-four new 1, 3-disubstituted urea derivatives (compounds 1–24) were synthesized
and reported for the first time. The antiproliferative activities of these compounds were …

Seven subsets of aromatic urea and amide analogues of N-phenyl-N′-(2-chloroethyl)
ureas (CEU) have been synthesized by nucleophilic addition of 3-chloropropylisocyanate, 2 …

Novel series of benzoylphenylurea analogs 7–10 were prepared and evaluated for in vitro
cytotoxic activity against a panel of eight different human cancer cell lines. A very interesting …

First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
23307982&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Ursolic acid (UA) is a pentacyclic triterpene isolated from a large variety of vegetables, fruits
and many traditional medicinal plants. It is a structural isomer of Oleanolic Acid. The …