Nanoparticles: oral delivery for protein and peptide drugs
S Cao, S Xu, H Wang, Y Ling, J Dong, R Xia, X Sun - Aaps Pharmscitech, 2019 - Springer
Protein and peptide drugs have many advantages, such as high bioactivity and specificity,
strong solubility, and low toxicity. Therefore, the strategies for improving the bioavailability of …
strong solubility, and low toxicity. Therefore, the strategies for improving the bioavailability of …
Polymeric nano-and microparticles for the oral delivery of peptides and peptidomimetics
E Allémann, JC Leroux, R Gurny - Advanced drug delivery reviews, 1998 - Elsevier
Due to recent advances, numerous bioactive peptides are now available in large quantities.
Administering these substances by the oral route appears as a formidable challenge due to …
Administering these substances by the oral route appears as a formidable challenge due to …
Nanoparticles for oral delivery: targeted nanoparticles with peptidic ligands for oral protein delivery
As the field of biotechnology has advanced, oral protein delivery has also made significant
progress. Oral delivery is the most common method of drug administration with high levels of …
progress. Oral delivery is the most common method of drug administration with high levels of …
Recent advances in protein and peptide drug delivery: a special emphasis on polymeric nanoparticles
Proteins and peptides are widely indicated in many diseased states. Parenteral route is the
most commonly em-ployed method of administration for therapeutic proteins and peptides …
most commonly em-ployed method of administration for therapeutic proteins and peptides …
Nanoencapsulation II. Biomedical applications and current status of peptide and protein nanoparticulate delivery systems
The concept of polymeric nanoparticles for the design of new drug delivery systems
emerged a few years ago, and recent rapid advances in nanotechnology have offered a …
emerged a few years ago, and recent rapid advances in nanotechnology have offered a …
Recent insights in the use of nanocarriers for the oral delivery of bioactive proteins and peptides
P Batista, PM Castro, AR Madureira, B Sarmento… - Peptides, 2018 - Elsevier
Bioactive proteins and peptides have been used with either prophylactic or therapeutic
purposes, presenting inherent advantages as high specificity and biocompatibility …
purposes, presenting inherent advantages as high specificity and biocompatibility …
How to design the surface of peptide-loaded nanoparticles for efficient oral bioavailability?
The oral administration of proteins is a current challenge to be faced in the field of
therapeutics. There is currently much interest in nanocarriers since they can enhance oral …
therapeutics. There is currently much interest in nanocarriers since they can enhance oral …
Oral delivery of therapeutic proteins and peptides: a review on recent developments
S Gupta, A Jain, M Chakraborty, JK Sahni, J Ali… - Drug …, 2013 - Taylor & Francis
Advent of recombinant technology in protein synthesis has given birth to a new range of
biopharmaceuticals. These therapeutic peptides and proteins are now emerging as an …
biopharmaceuticals. These therapeutic peptides and proteins are now emerging as an …
Design of nanoparticles composed of graft copolymers for oral peptide delivery
S Sakuma, M Hayashi, M Akashi - Advanced drug delivery reviews, 2001 - Elsevier
The development of a dosage form that improves the absorption of peptide and protein
drugs via the gastrointestinal tract is one of the greatest challenges in the pharmaceutical …
drugs via the gastrointestinal tract is one of the greatest challenges in the pharmaceutical …
Peptide and protein delivery using new drug delivery systems
Pharmaceutical and biotechnological research sorts protein drug delivery systems by
importance based on their various therapeutic applications. The effective and potent action …
importance based on their various therapeutic applications. The effective and potent action …