Biodegradable polymeric occluder for closure of atrial septal defect with interventional treatment of cardiovascular disease

B Li, Z Xie, Q Wang, X Chen, Q Liu, W Wang, Y Shen… - Biomaterials, 2021 - Elsevier
The next-generation closure device for interventional treatment of congenital heart disease
is regarded to be biodegradable, yet the corresponding biomaterial technique is still …

Novel biodegradable polycaprolactone occlusion device combining nanofibrous PLGA/collagen membrane for closure of atrial septal defect (ASD)

SJ Liu, KM Peng, CY Hsiao, KS Liu, HT Chung… - Annals of biomedical …, 2011 - Springer
The purpose of this report was to develop novel biodegradable occlusion devices for closure
of atrial septal defects (ASD). To manufacture the biodegradable occluders …

Study of biodegradable occluder of atrial septal defect in a porcine model

BN Li, YM Xie, ZF Xie, XM Chen… - Catheterization and …, 2019 - Wiley Online Library
Objective To evaluate the safety and feasibility of a modified poly (l‐lactic acid)(PLLA) atrial
septal defect (ASD) occluder. Methods Forty‐five piglets were divided into two groups: an …

A Novel Biodegradable Septal Defect Occluder the “Chinese Lantern” Design, Proof of Concept

W Wu, J Yip, YD Tang, V Khoo, JF Kong… - …, 2011 - journals.sagepub.com
Objective Atrial septal defect (ASD) is a general term used to describe an opening in the
atrial septum that divides the two atria; unless the hole is occluded, it can give rise to serious …

Biodegradable atrial septal defect occluders: a current review

D Shi, Y Kang, G Zhang, C Gao, W Lu, H Zou, H Jiang - Acta Biomaterialia, 2019 - Elsevier
Atrial septal defect (ASD) is a common structural congenital heart disease. With the
development of interventional closure devices and transcatheter techniques, interventional …

[HTML][HTML] Animal experimental study of the fully biodegradable atrial septal defect (ASD) occluder

Y Zhu, X Huang, J Cao, J Hu, Y Bai, H Jiang… - BioMed Research …, 2012 - hindawi.com
This study was conducted to evaluate the feasibility, safety, biocompatibility, and
degradation features of a fully biodegradable occluder for closure of atrial septal defect …

Interventional atrial septal defect closure using a totally bioresorbable occluder matrix: development and preclinical evaluation of the BioSTAR device

C Jux, H Bertram, P Wohlsein, M Bruegmann… - Journal of the American …, 2006 - jacc.org
Objectives: We sought to test the hypothesis that interventional atrial septal defect (ASD)
closure can be performed safely and effectively using a bioresorbable occluder matrix …

Development and preclinical evaluation of a biodegradable ventricular septal defect occluder

X Huang, Y Zhu, J Cao, J Hu, Y Bai… - Catheterization and …, 2013 - Wiley Online Library
Objectives This study evaluated the feasibility, effectiveness, and safety of a biodegradable
(BD) occluder for closure of ventricular septal defect (VSD) in an acute canine model …

[HTML][HTML] 3D printing and biocompatibility study of a new biodegradable occluder for cardiac defect

Y Sun, X Zhang, W Li, Y Di, Q Xing, Q Cao - Journal of Cardiology, 2019 - Elsevier
Objective To fabricate a biodegradable occluder for heart defect using the three-dimensional
(3D) printing technique and evaluate its biosafety in an animal model. Methods Occluder …

Recent developments in next-generation occlusion devices

C Lin, L Liu, Y Liu, J Leng - Acta Biomaterialia, 2021 - Elsevier
Transcatheter closure has been widely accepted as a highly effective way to treat abnormal
blood flows and/or embolization of thrombus in the heart. It allows the closure of four types of …