Role of exosomes in tumour growth, chemoresistance and immunity: state-of-the-art

SM Hosseinikhah, F Gheybi, SA Moosavian… - Journal of Drug …, 2023 - Taylor & Francis
Cancer is one of the most lethal diseases, and limited available treatment options contribute
to its high mortality rate. Exosomes are considered membrane-bound nanovesicles that …

The biological function and therapeutic potential of exosomes in cancer: exosomes as efficient nanocommunicators for cancer therapy

JU Choi, IK Park, YK Lee, SR Hwang - International journal of molecular …, 2020 - mdpi.com
Cancer therapeutics must be delivered to their targets for improving efficacy and reducing
toxicity, though they encounter physiological barriers in the tumor microenvironment. They …

Exosomes harnessed as nanocarriers for cancer therapy-current status and potential for future clinical applications

TU Wani, R Mohi-Ud-Din, RH Mir… - Current molecular …, 2021 - ingentaconnect.com
Exosomes are nano structured (50-90 nm) vesicles that originate from endosomal
compartment of eukaryotic cells and are secreted into extracellular matrix. In recent years …

[HTML][HTML] The exosome journey: from biogenesis to regulation and function in cancers

Y Li, L Meng, B Li, Y Li, T Shen, B Zhao - Journal of Oncology, 2022 - hindawi.com
Exosomes are a type of small endosomal-derived vesicles ranging from 30 to 150 nm, which
can serve as functional mediators in cell-to-cell communication and various physiological …

Protein cargo in extracellular vesicles as the key mediator in the progression of cancer

K Hánělová, M Raudenská, M Masařík… - Cell Communication and …, 2024 - Springer
Exosomes are small vesicles of endosomal origin that are released by almost all cell types,
even those that are pathologically altered. Exosomes widely participate in cell-to-cell …

[HTML][HTML] Exosomes and mimics as novel delivery platform for cancer therapy

F Yang, M Wang, X Guan - Frontiers in Pharmacology, 2022 - frontiersin.org
Exosomes are nano-sized biological extracellular vesicles transmitting information between
cells and constituting a new intercellular communication mode. Exosomes have many …

Roles of exosomes in cancer chemotherapy resistance, progression, metastasis and immunity, and their clinical applications

X Wang, Y Zhou, K Ding - International journal of …, 2021 - spandidos-publications.com
Exosomes are a type of vesicle that are secreted by cells, with a diameter of 40‑100 nm, and
that appear as a cystic shape under an electron microscope. Exosome cargo includes a …

Exosomes: new biomarkers for targeted cancer therapy

C Martinelli - Molecular oncology: Underlying mechanisms and …, 2017 - Springer
Exosomes have emerged as novel and important mediators of intercellular communication.
They contain bioactive molecules including proteins, DNA, mRNA and miRNA, which are …

[HTML][HTML] Exosomes: Small vesicles with big roles in cancer, vaccine development, and therapeutics

A Thakur, DC Parra, P Motallebnejad, M Brocchi… - Bioactive materials, 2022 - Elsevier
Cancer is a deadly disease that is globally and consistently one of the leading causes of
mortality every year. Despite the availability of chemotherapy, radiotherapy, immunotherapy …

Exosomes and cancer: from molecular mechanisms to clinical applications

A Jafari, A Babajani, M Abdollahpour-Alitappeh… - Medical Oncology, 2021 - Springer
Exosomes are extracellular nanovesicles secreted from almost all types of normal and
cancer cells. Collective evidence suggests that exosomes participate in cell–cell …