A number of inherited disorders result in renal cyst development. The most common form,
autosomal dominant polycystic kidney disease (ADPKD), is a disorder most often diagnosed …

Initiation of cyst formation in autosomal dominant polycystic kidney disease (ADPKD) occurs
when kidney tubule cells are rendered null for either PKD1 or PKD2 by somatic 'second …

Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic
disease, affecting a half million Americans. The clinical phenotype can result from at least …

Autosomal dominant polycystic kidney disease (ADPKD), the most frequent cause of genetic
renal disease affecting approximately 4 to 7 million individuals worldwide and accounting for …

Autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive
polycystic kidney disease (ARPKD) are important inherited kidney diseases with distinct …

An intriguing feature of autosomal dominant polycystic kidney disease (ADPKD) is the focal
and sporadic formation of renal and extrarenal cysts. Recent documentation of somatic …

Autosomal dominant polycystic kidney disease is an important cause of end-stage renal
disease, for which there is no proven therapy. Mutations in PKD1 (the gene encoding …

Autosomal dominant polycystic disease (ADPKD) is the most common form of inherited
kidney disease that results in renal failure. The understanding of the pathogenesis of …

Autosomal dominant polycystic kidney disease (ADPKD), the most common monogenic
cause of ESKD, is characterized by relentless development of kidney cysts, hypertension …

Autosomal dominant polycystic kidney disease (ADPKD) is the most common Mendelian
disorder of the kidney and affects all racial groups worldwide. It is characterized by focal …