Mesenchymal stem cells: The roles and functions in cutaneous wound healing and tumor growth

SI Motegi, O Ishikawa - Journal of Dermatological Science, 2017 - Elsevier
Mesenchymal stem cells (MSCs) are bone marrow-derived non-hematopoietic progenitor
cells. MSCs are able to differentiate into various types of cells, including chondrocytes …

Mechanisms of action of mesenchymal stem cells in cutaneous wound repair and regeneration

HH Li, X Fu - Cell and Tissue Research, 2012 - Springer
Mesenchymal stem cells (MSCs) are multipotent cells with the capacity for self-renewal and
differentiation and have a broad tissue distribution. These characteristics make them …

Mesenchymal stem cells and skin wound repair and regeneration: possibilities and questions

X Fu, H Li - Cell and tissue research, 2009 - Springer
Adult mesenchymal stem cells (MSCs) have the capacity for self-renewal and for
differentiating into a variety of cells and tissues. They may leave their niche to migrate to …

Mesenchymal stem cells: paracrine signaling and differentiation during cutaneous wound repair

AM Hocking, NS Gibran - Experimental cell research, 2010 - Elsevier
Cutaneous wounds persist as a health care crisis in spite of increased understanding of the
cellular and molecular responses to injury. Contributing significantly to this crisis is the lack …

Mesenchymal stem cells and cutaneous wound healing: novel methods to increase cell delivery and therapeutic efficacy

DE Lee, N Ayoub, DK Agrawal - Stem cell research & therapy, 2016 - Springer
Mesenchymal stem cells (MSCs)(also known as multipotent mesenchymal stromal cells)
possess the capacity for self-renewal and multi-lineage differentiation, and their ability to …

Mesenchymal stem cells and cutaneous wound healing: current evidence and future potential

M Isakson, C De Blacam, D Whelan… - Stem cells …, 2015 - Wiley Online Library
Human skin is a remarkable organ that sustains insult and injury throughout life. The ability
of skin to expeditiously repair wounds is paramount to survival. With an aging global …

Topical delivery of mesenchymal stem cells and their function in wounds

JM Sorrell, AI Caplan - Stem cell research & therapy, 2010 - Springer
Mesenchymal stem cells are a heterogeneous population of fibroblast-like cells found in
most adult organs. However, most of our current knowledge is based on cells of bone …

Mesenchymal stem cells in chronic wounds: the spectrum from basic to advanced therapy

M Otero-Viñas, V Falanga - Advances in Wound Care, 2016 - liebertpub.com
Significance: Almost 7 million Americans have chronic cutaneous wounds and billions of
dollars are spent on their treatment. The number of patients with nonhealing wounds keeps …

Concise review: role of mesenchymal stem cells in wound repair

S Maxson, EA Lopez, D Yoo… - Stem cells …, 2012 - academic.oup.com
Wound healing requires a coordinated interplay among cells, growth factors, and
extracellular matrix proteins. Central to this process is the endogenous mesenchymal stem …

Mesenchymal stromal cells and cutaneous wound healing: a comprehensive review of the background, role, and therapeutic potential

MS Hu, MR Borrelli, HP Lorenz… - Stem cells …, 2018 - Wiley Online Library
Cutaneous wound repair is a highly coordinated cascade of cellular responses to injury
which restores the epidermal integrity and its barrier functions. Even under optimal healing …