Age and ovariectomy abolish beneficial effects of female sex on rat ventricular myocytes exposed to simulated ischemia and reperfusion
JL Ross, SE Howlett - PLoS One, 2012 - journals.plos.org
Sex differences in responses to myocardial ischemia have been described, but whether
cardiomyocyte function is influenced by sex in the setting of ischemia and reperfusion has …
cardiomyocyte function is influenced by sex in the setting of ischemia and reperfusion has …
Effect of 6-wk estrogen withdrawal or replacement on myocardial ischemic tolerance in rats
PH McNulty, D Jagasia, JM Whiting… - American Journal of …, 2000 - journals.physiology.org
Menopausal status is a risk factor for coronary artery disease death, but the mechanism
underlying this association is uncertain. To test whether estrogen ameliorates the effects of …
underlying this association is uncertain. To test whether estrogen ameliorates the effects of …
Ischemic heart disease and cardioprotection: Focus on estrogenic hormonal setting and microvascular health
G Querio, S Antoniotti, F Geddo, F Tullio, C Penna… - Vascular …, 2021 - Elsevier
Abstract Ischemic Heart Disease (IHD) is a clinical condition characterized by insufficient
blood flow to the cardiac tissue, and the consequent inappropriate oxygen and nutrients …
blood flow to the cardiac tissue, and the consequent inappropriate oxygen and nutrients …
The biological impact of estrogens on gender differences in congestive heart failure
G Schönfelder - Cardiovascular research, 2005 - academic.oup.com
Heart failure seems to be a different entity in women than in men because of gender-related
differences in the cardiovascular system. Myocardial hypertrophy is one independent risk …
differences in the cardiovascular system. Myocardial hypertrophy is one independent risk …
Gender specific effect of progesterone on myocardial ischemia/reperfusion injury in rats
VV Dhote, R Balaraman - Life Sciences, 2007 - Elsevier
The study was designed to investigate the effect of progesterone and its gender based
variation on myocardial ischemia/reperfusion (I/R) injury in rats. Adult Sprague Dawley rats …
variation on myocardial ischemia/reperfusion (I/R) injury in rats. Adult Sprague Dawley rats …
The stronger sex, until menopause: understanding the impact of estrogen loss on heart function
CK Conway-O'Donnell… - American Journal of …, 2022 - journals.physiology.org
In the first four decades of life, women are protected from cardiovascular disease (CVD)
compared with men, perhaps making women the stronger sex. Over the next five to ten …
compared with men, perhaps making women the stronger sex. Over the next five to ten …
Medroxyprogesterone acetate aggravates oxidative stress and left ventricular dysfunction in rats with chronic myocardial infarction
PA Arias-Loza, K Hu, S Frantz… - Toxicologic …, 2011 - journals.sagepub.com
The role of estrogens during myocardial ischemia has been extensively studied. However,
effects of a standard hormone replacement therapy including 17β-estradiol (E2) combined …
effects of a standard hormone replacement therapy including 17β-estradiol (E2) combined …
A systematic review and meta-analysis of phytoestrogen protects against myocardial ischemia/reperfusion injury: Pre-clinical evidence from small animal studies
Y Wang, X Shou, Z Fan, J Cui, D Xue… - Frontiers in …, 2022 - frontiersin.org
Background: Phytoestrogens are a class of natural compounds that have structural
similarities to estrogens. They have been identified to confer potent cardioprotective effects …
similarities to estrogens. They have been identified to confer potent cardioprotective effects …
Evidence against a role of physiological concentrations of estrogen in post-myocardial infarction remodeling
S Hügel, M Reincke, H Strömer, J Winning… - Journal of the American …, 1999 - jacc.org
OBJECTIVES The purpose of this study was to examine whether endogenous estrogen
deficiency induced by ovariectomy affects chronic left ventricular dysfunction post …
deficiency induced by ovariectomy affects chronic left ventricular dysfunction post …
The role of estrogen and estrogen-related drugs in cardiovascular diseases
H Ogita, K Node, M Kitakaze - Current drug metabolism, 2003 - ingentaconnect.com
The cardiovascular effects of estrogen have recently become a focus of basic and clinical
cardiovascular medicine because of the multiplicity of its beneficial effects. Various basic …
cardiovascular medicine because of the multiplicity of its beneficial effects. Various basic …