drug‐induced liver injury in the context of nonalcoholic fatty liver disease–a physiopathological and clinical integrated view

F Bessone, M Dirchwolf, MA Rodil… - Alimentary …, 2018 - Wiley Online Library
Background Nonalcoholic fatty disease (NAFLD) is the most common liver disease, since it
is strongly associated with obesity and metabolic syndrome pandemics. NAFLD may affect …

A prospective study of acute drug‐induced liver injury in patients suffering from non‐alcoholic fatty liver disease

G Tarantino, P Conca, V Basile, A Gentile… - Hepatology …, 2007 - Wiley Online Library
Aim: Liver damage due to facultative hepatotoxins is scarcely foreseeable. We evaluated the
prevalence of acute drug‐induced liver injury (DILI) in a specific setting, assessing eventual …

Drug induced steatohepatitis: an uncommon culprit of a common disease

L Rabinowich, O Shibolet - BioMed research international, 2015 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a leading cause of liver disease in developed
countries. Its frequency is increasing in the general population mostly due to the widespread …

Drug-induced liver injury in obesity and nonalcoholic fatty liver disease

J Allard, D Le Guillou, K Begriche… - Advances in Pharmacology, 2019 - Elsevier
Obesity is commonly associated with nonalcoholic fatty liver (NAFL), a benign condition
characterized by hepatic lipid accumulation. However, NAFL can progress in some patients …

[HTML][HTML] Drug-induced fatty liver disease: Pathogenesis and treatment

TO Kolaric, V Nincevic, L Kuna, K Duspara… - Journal of clinical and …, 2021 - ncbi.nlm.nih.gov
Metabolic dysfunction-associated fatty liver disease (commonly known as MAFLD) impacts
global health in epidemic proportions, and the resulting morbidity, mortality and economic …

[PDF][PDF] Fatty liver and drugs: the two sides of the same coin.

L Miele, A Liguori, G Marrone, M Biolato… - European Review for …, 2017 - europeanreview.org
Drug-induced liver injury (DILI) is a common and underestimated cause of liver disease.
Several drugs and other xenobiotics can be the cause of different clinicopathologic patterns …

[HTML][HTML] Drug-induced fatty liver disease: An overview of pathogenesis and management

SK Satapathy, V Kuwajima, J Nadelson, O Atiq… - Annals of hepatology, 2015 - Elsevier
Over the past decades, many drugs have been identified, that can potentially induce
steatohepatitis in the predisposed individual. Classically this has been incriminated to …

Drug-induced liver injury in obesity

B Fromenty - Journal of hepatology, 2013 - journal-of-hepatology.eu
Many countries are facing an epidemic of obesity that can be explained, at least in part, by a
sedentary life style and calorie overconsumption. This poses a major issue for public health …

Triglycerides in nonalcoholic fatty liver disease: guilty until proven innocent

I Semova, SB Biddinger - Trends in pharmacological sciences, 2021 - cell.com
End-stage liver disease (ESLD) is a rare but often fatal complication of nonalcoholic fatty
liver disease (NAFLD). In NAFLD, insulin resistance, which is clinically defined as the …

Drug-induced steatohepatitis

A Dash, RA Figler, AJ Sanyal… - Expert opinion on drug …, 2017 - Taylor & Francis
Introduction: Drug induced steatohepatitis (DISH), a form of drug induced liver injury (DILI) is
characterized by intracellular accumulation of lipids in hepatocytes and subsequent …