Estimation of the cost-effectiveness of apixaban versus vitamin K antagonists in the management of atrial fibrillation in Argentina

MA Giorgi, C Caroli, ND Giglio, P Micone… - Health Economics …, 2015 - Springer
Apixaban, a novel oral anticoagulant which has been approved for the prevention of stroke
and systemic embolism in non-valvular atrial fibrillation, reduces both ischemic and …

Efficacy and safety of apixaban compared with warfarin according to patient risk of stroke and of bleeding in atrial fibrillation: a secondary analysis of a randomised …

RD Lopes, SM Al-Khatib, L Wallentin, H Yang, J Ansell… - The Lancet, 2012 - thelancet.com
Summary Background The Apixaban for Reduction in Stroke and Other Thromboembolic
Events in Atrial Fibrillation (ARISTOTLE) trial showed that apixaban is better than warfarin at …

Efficacy and safety of apixaban compared with warfarin at different levels of predicted international normalized ratio control for stroke prevention in atrial fibrillation

L Wallentin, RD Lopes, M Hanna, L Thomas… - Circulation, 2013 - Am Heart Assoc
Background—In the Apixaban for Reduction in Stroke and Other Thromboembolic Events in
Atrial Fibrillation (ARISTOTLE) trial, apixaban compared with warfarin reduced stroke and …

Comparative effectiveness and safety of apixaban and vitamin K antagonist therapy in patients with nonvalvular atrial fibrillation treated in routine German practice

CI Coleman, WF Peacock, M Antz - Heart, Lung and Circulation, 2018 - Elsevier
Background Scarce data comparing real-world outcomes between apixaban and vitamin K
antagonist (VKA) users with nonvalvular atrial fibrillation (NVAF) are available. We sought to …

[HTML][HTML] Apixaban versus warfarin in patients with atrial fibrillation

CB Granger, JH Alexander, JJV McMurray… - … England Journal of …, 2011 - Mass Medical Soc
Background Vitamin K antagonists are highly effective in preventing stroke in patients with
atrial fibrillation but have several limitations. Apixaban is a novel oral direct factor Xa …

Apixaban for stroke prevention in atrial fibrillation: why are event rates higher in clinical practice than in randomized trials?—a systematic review

TAC de Vries, J Hirsh, K Xu, I Mallick… - Thrombosis and …, 2020 - thieme-connect.com
Background Recent reports suggest an important contribution from frequent off-label use of
apixaban 2.5 mg twice daily to the higher rates of thromboembolic events observed in …

Efficacy and safety of apixaban compared with warfarin according to age for stroke prevention in atrial fibrillation: observations from the ARISTOTLE trial

S Halvorsen, D Atar, H Yang… - European heart …, 2014 - academic.oup.com
Aims The risk of stroke in patients with atrial fibrillation (AF) increases with age. In the
ARISTOTLE trial, apixaban when compared with warfarin reduced the rate of stroke, death …

Cost-effectiveness of apixaban, dabigatran, rivaroxaban, and warfarin for stroke prevention in atrial fibrillation

AR Harrington, EP Armstrong, PE Nolan Jr, DC Malone - Stroke, 2013 - Am Heart Assoc
Background and Purpose—To estimate the cost-effectiveness of stroke prevention in
patients with nonvalvular atrial fibrillation by using novel oral anticoagulants apixaban 5 mg …

Outcomes of apixaban vs. warfarin by type and duration of atrial fibrillation: results from the ARISTOTLE trial

SM Al-Khatib, L Thomas, L Wallentin… - European heart …, 2013 - academic.oup.com
Aims It is uncertain whether the benefit from apixaban varies by type and duration of atrial
fibrillation (AF). Methods and results A total of 18 201 patients with AF [2786 (15.3%) with …

Effectiveness and safety of apixaban in over 3.9 million people with atrial fibrillation: a systematic review and meta-analysis

BJR Buckley, DA Lane, P Calvert, J Zhang… - Journal of clinical …, 2022 - mdpi.com
Background: There is a plethora of real-world data on the safety and effectiveness of direct-
acting oral anticoagulants (DOACs); however, study heterogeneity has contributed to …