Purpose Existence and cause of thyroid stunning was controversially discussed for decades
but the underlying mechanism remains unclear. Numerous studies describe thyroid stunning …

Purpose Radioiodine-131 treatment has been a well-established therapy for benign thyroid
diseases for more than 75 years. However, the physiological reasons of the so-called …

Debates regarding thyroid stunning—a phenomenon whereby a diagnostic dose of
radioiodine decreases uptake of a subsequent therapeutic dose by remnant thyroid tissue or …

In radioiodine therapy of benign thyroid disease, a reduction of radioiodine uptake is known
for consecutive administrations of 131 I, which needs to be considered in therapy planning …

With regard to the treatment of differentiated non-medullary thyroid carcinoma, there is
controversy over whether radiation from a diagnostic radioiodine (131 I) application really …

Thyroid stunning is a radiobiological phenomenon. It may be defined as a temporary
suppression of iodine, trapping function of the thyrocytes and thyroid cancer cells as a result …

Radioiodine (RAI) is becoming the preferred treating option for benign thyroid diseases.
Hyperthyroidism is defined as hypermetabolic state caused by high levels of circulating …

Aim To review published in-vivo and in-vitro quantitative dosimetric studies on thyroid
stunning in order to derive novel data applicable in clinical practice. Methods A non-linear …

Despite a significantly improved dietary iodine supply, solitary toxic thyroid nodules (STN)
are still a common clinical problem in former iodine deficient areas. Radioiodine treatment …

Objective: Current guidelines have advised against the performance of 131I-iodide
diagnostic whole body scintigraphy (dxWBS) to minimize the occurrence of stunning, and to …